PMID: 43104Oct 1, 1979

Induction of acid-stable canine interferon in vivo and in vitro

American Journal of Veterinary Research
M S FormanW Turner

Abstract

Dogs were able to produce only small quantities of circulating interferon after intraperitonal injection of Newcastle disease virus or polyinosinic-polycytidylic acid. Similarly, canine cell cultures produced very low concentrations of interferon in response to Newcastle disease virus or polyinosinic-polycytidylic acid and no detectable concentrations of interferon in response to pyran copolymer or tilorone hydrochloride. The antiviral substance met the physiochemical characteristics classically associated with interferon.

Related Concepts

Newcastle disease virus
Cell Culture Techniques
Human leukocyte interferon
Interferon
Tilorone Hydrochloride
Body Surface Area Formula for Dogs
Interferons
Newcastle Disease
Dog family
Hydrogen-Ion Concentration

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