PMID: 3768431Oct 31, 1986Paper

Induction of adipose S-100 protein release by free fatty acids in adipocytes

Biochimica Et Biophysica Acta
F Suzuki, K Kato

Abstract

The mechanism of S-100 protein release from adipocytes, which is apparently coupled with lipolytic activity, was investigated in vitro using rat epididymal fat pads. The S-100 protein release was increased severalfold by 10 microM epinephrine in the medium containing a low concentration (less than 5 mg/ml) of albumin, but the release was enhanced only slightly when the medium contained a high concentration (more than 20 mg/ml) of albumin. On the other hand, the maximum rate of free fatty acid release measured simultaneously was observed in medium containing more than 20 mg/ml albumin. The rate of S-100 protein release was found to be closely related to the concentrations of both albumin added to the incubation medium and fatty acids released into it, and the rate was increased under conditions wherein the molar ratio of fatty acid/albumin was greater than 6. The S-100 protein release from fat pads was also enhanced solely by the addition of an excess amount (6 mM) of palmitic acid or oleic acid. The basal release of S-100 protein at a high concentration of albumin in the fat pads of diabetic or long-term starved rats, in which the fatty acid level in adipocytes is known to be enhanced, was about 7- and 2-fold higher, respective...Continue Reading

References

May 30, 1985·Biochimica Et Biophysica Acta·F Suzuki, K Kato
Oct 17, 1985·Biochimica Et Biophysica Acta·K Kato, S Kimura
Oct 8, 1965·Annals of the New York Academy of Sciences·M Rodbell
Jun 9, 1965·Biochemical and Biophysical Research Communications·B W Moore
Nov 1, 1984·Journal of Neurochemistry·F SuzukiT Nakajima
Sep 1, 1983·Journal of Biochemistry·K KatoT Nakajima
Sep 1, 1982·Journal of Biochemistry·F SuzukiK Kato
Jan 1, 1983·Journal of Biochemistry·K KatoT Nakajima
Jan 7, 1982·Nature·K StefanssonB G Arnason
May 1, 1981·European Journal of Biochemistry·T Isobe, T Okuyama
Oct 1, 1980·Analytical Biochemistry·K MizunoH Hirakawa
Feb 1, 1956·The Journal of Clinical Investigation·V P DOLE
Feb 1, 1960·The Journal of Clinical Investigation·M S RABEN, C H HOLLENBERG

❮ Previous
Next ❯

Citations

Jan 5, 2000·The Annals of Thoracic Surgery·P M Bokesch
Jul 31, 2010·Cardiovascular Psychiatry and Neurology·Carlos Alberto GonçalvesMaria Cristina Guerra
Jun 28, 2013·Obesity·Atsushi FujiyaYoji Hamada
Jun 2, 2001·Scandinavian Journal of Clinical and Laboratory Investigation·L M YtrebøA Revhaug
May 11, 2021·Neuroscience and Biobehavioral Reviews·Fabrizio MichettiFrancesco Ria

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Clinical Chemistry and Clinical Biochemistry. Zeitschrift Für Klinische Chemie Und Klinische Biochemie
K D GerbitzK Mross
© 2021 Meta ULC. All rights reserved