Induction of anaesthesia with alfaxalone or propofol before isoflurane maintenance in cats

The Veterinary Record
F Martinez Taboada, P J Murison

Abstract

Thirty-nine healthy cats that were presented for ovariohysterectomy received intramuscular acepromazine (0.05 mg/kg) and subcutaneous meloxicam (0.3 mg/kg) as preanaesthetic medication. They were then randomly assigned to receive either propofol or alfaxalone by intravenous injection for induction of anaesthesia, administered to effect until tracheal intubation was possible. Anaesthesia was maintained with isoflurane in oxygen. Cardiorespiratory variables were measured before induction and every five minutes throughout anaesthesia. The recovery times and quality of recovery were also recorded. Data relating to one cat were omitted because it was found to be pregnant. The mean (sd) induction doses were 4.7 (1.2) mg/kg for alfaxalone and 7.5 (2.0) mg/kg for propofol. Postinduction apnoea was not observed. There were no significant differences in cardiorespiratory variables between the alfaxalone group (mean pulse rate [PR] 155 [18]) bpm, Doppler arterial blood pressure [DBP] 73 [6] mmHg, respiratory rate [RR] 31 [8] breaths/minute, end-tidal carbon dioxide partial pressure [PECO(2)] 3.7 [0.8] kPa) and the propofol group (PR 147 [16] bpm, DBP 77 [12] mmHg, RR 32 [8] breaths/minute, PECO(2) 3.7 [0.5] kPa). Recovery times were very ...Continue Reading

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Citations

Sep 26, 2013·Journal of Zoo and Wildlife Medicine : Official Publication of the American Association of Zoo Veterinarians·Larry J MinterLysa P Posner
Aug 24, 2012·Veterinary Surgery : VS·Pieter NelissenRichard A S White
Aug 13, 2011·Veterinary Anaesthesia and Analgesia·Mads F Bertelsen, Cathrine D Sauer
Jan 22, 2013·Veterinary Anaesthesia and Analgesia·Jill K ManeyErik H Hofmeister
Apr 25, 2013·Veterinary Anaesthesia and Analgesia·Enzo Vettorato
Apr 11, 2012·Veterinary Anaesthesia and Analgesia·Alessandra MathisHatim I K Alibhai
May 20, 2014·Veterinary Anaesthesia and Analgesia·Ana M del ÁlamoMark E Payton
Mar 29, 2014·Veterinary Anaesthesia and Analgesia·Karin S Kalchofner GuerreroRegula Bettschart-Wolfensberger
Apr 24, 2014·Veterinary Anaesthesia and Analgesia·Larry J MinterLysa P Posner
Oct 14, 2014·Veterinary Anaesthesia and Analgesia·Ivo CampagnaMartina Mosing
Dec 11, 2013·The Veterinary Journal·Kuan Hua KhorPaul C Mills
Nov 30, 2014·The Veterinary Record·Minh HuynhLuca Zilberstein
Jan 15, 2015·The Veterinary Journal·Leon N WarneSébastien H Bauquier
Jul 13, 2016·Journal of Feline Medicine and Surgery·Latifa KhenissiGwenola Touzot-Jourde
Dec 21, 2014·Journal of Feline Medicine and Surgery·Marieke de Vries, Gerhard Putter
Dec 7, 2013·Journal of Feline Medicine and Surgery·Thierry BethsKirby Pasloske
Sep 18, 2015·Journal of Feline Medicine and Surgery·Sébastien H BauquierThierry Beths
Aug 30, 2017·The Veterinary Record·Sandra D TaylorAudrey Ruple
Jun 1, 2018·Journal of Feline Medicine and Surgery·David M NeilsonSandra Sanchis-Mora
Nov 5, 2013·Anaesthesia and Intensive Care·J Carter, D A Story
Nov 28, 2017·Journal of Feline Medicine and Surgery·Renato Ls OliveiraHeloisa Jm Souza
Mar 9, 2018·Journal of Zoo and Wildlife Medicine : Official Publication of the American Association of Zoo Veterinarians·Catherine J A WilliamsTobias Wang
Mar 20, 2015·The Journal of Veterinary Medical Science·Jun TamuraKazuto Yamashita
Nov 28, 2014·The Journal of Veterinary Medical Science·Jun TamuraKazuto Yamashita
Oct 27, 2020·Journal of Feline Medicine and Surgery·Bradley T Simon, Paulo V Steagall
Nov 18, 2017·Veterinary Anaesthesia and Analgesia·Sarah E BigbyJennifer E Carter
Jul 8, 2017·Veterinary Anaesthesia and Analgesia·Julia DeutschElizabeth A Leece

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