PMID: 11315168Apr 21, 2001Paper

Induction of anaesthesia with desflurane and isoflurane in the rabbit

Laboratory Animals
P HedenqvistP A Flecknell

Abstract

The characteristics of two techniques of face-mask induction of desflurane anaesthesia (rapid or slow) were compared with the effects of slow isoflurane induction in five New Zealand White (NZW) rabbits. Slow induction used stepwise increments in vapour setting of 2% for desflurane and 0.5% for isoflurane at 30 s intervals. All animals were anaesthetized using each technique according to a randomized block design with one week between treatments. Observations were made of the quality of induction (any struggling or periods of apnoea) and the latency to, and the duration of loss of the righting and toe pinch reflexes recorded. Changes in respiratory rate, arterial blood gas and cardiovascular parameters were also recorded. Induction and recovery times were shorter with rapid desflurane induction in comparison to isoflurane (loss of righting reflex: 139+/-27 s cf. 205+/-48 s), but both techniques were associated with struggling and long periods of apnoea (> 1 min) during the first 4 min after administration. During this period a significant degree of bradycardia, hypercapnia and hypoxaemia occurred with both techniques, but these and the subsequent effects of rapid desflurane administration were less severe than with isoflurane. ...Continue Reading

Citations

Oct 4, 2006·American Journal of Veterinary Research·Ana Patrícia N Fontes-SousaAdelino F Leite-Moreira
Jul 16, 2014·Zeitschrift für medizinische Physik·Nadja M MeßnerLothar R Schad
Oct 15, 2014·Experimental Animals·Atsushi TsukamotoTomo Inomata
Sep 2, 2005·Veterinary Anaesthesia and Analgesia·Hannah E OrrPaul A Flecknell
Mar 17, 2010·Veterinary Anaesthesia and Analgesia·Kathy L MurphyPaul A Flecknell
Feb 4, 2010·Acta Cirúrgica Brasileira·Rosi Pereira BalbinottoRodrigo da Silva
Jan 15, 2010·Laboratory Animals·Sandra AllweilerPaul A Flecknell
Jun 27, 2018·American Journal of Veterinary Research·Nicolò ColumbanoGiovanni M Careddu
Jan 27, 2009·The Veterinary Record·M K MarshS K Maloney

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bradyarrhythmias

Bradyarrhythmias are slow heart rates. Symptoms may include syncope, dizziness, fatigure, shortness of breath, and chest pains. Find the latest research on bradyarrhythmias here.