Induction of burst-suppression and activation of epileptiform activity after methohexital and selective amygdalo-hippocampectomy

Electroencephalography and Clinical Neurophysiology
Richard WennbergF Dubeau

Abstract

Electrocorticography (ECOG) compared the effects of methohexital (MTH) and selective amygdalo-hippocampectomy (selAH) upon lateral temporal neocortical epileptiform activity (EA) in 31 patients with mesial temporal epilepsy. Pre-excision ECOG showed independent neocortical EA before MTH in 12/31 and after MTH in 18/31. MTH (20-50 mg) activated neocortical EA in 12 cases and induced burst-suppression (BS) over temporal neocortex in 14/31. Post-excision ECOG showed neocortical EA in 21/31 and BS in 27/31: compared with pre-excision ECOG before MTH, selAH activated neocortical EA in 15 cases. Significant correlations were found between presence of pre-excisional neocortical EA and presence of post-excisional neocortical EA (P < 0.001) and between activation of pre-excisional neocortical EA by MTH and activation of (post-excisional) neocortical EA by selAH (P < 0.006). Presence or severity of BS in the post-excision ECOG was not correlated with presence, absence or activation of post-excisional EA. Presence of neocortical EA was significantly correlated with a higher pre-operative seizure frequency (P < 0.001) but not with duration of epilepsy nor surgical outcome. Both MTH and selAH can induce neocortical BS, likely through chemic...Continue Reading

References

Jan 1, 1991·Trends in Neurosciences·J Kulli, C Koch
Mar 1, 1986·Electroencephalography and Clinical Neurophysiology·M R SperlingP H Crandall
Jan 1, 1988·International Anesthesiology Clinics·R W Olsen
Sep 1, 1989·Journal of Neurology, Neurosurgery, and Psychiatry·C E PolkeyI Janota
Jan 1, 1989·Journal of Neurology·J AaslyB Zetterlund
Apr 1, 1985·Archives of Neurology·F Morrell
Sep 1, 1967·Electroencephalography and Clinical Neurophysiology·L T RutledgeJ A Duncan
Dec 1, 1982·Anesthesia and Analgesia·E W FordW W Whisler
Jun 1, 1982·Surgical Neurology·H G Wieser, M G Yaşargil
Jan 1, 1994·Electroencephalography and Clinical Neurophysiology·M SteriadeD Contreras
Oct 1, 1993·Electroencephalography and Clinical Neurophysiology·A Yli-HankalaL Lindgren
Oct 1, 1994·Neuropediatrics·V JänttiG A Baer
Jan 1, 1952·Transactions of the American Neurological Association·F A ECHLIND PECK
Nov 1, 1957·Electroencephalography and Clinical Neurophysiology·B GRAFSTEIN, P B SASTRY
Jan 1, 1958·Psychiatria Et Neurologia·C HABERLAND
Nov 1, 1959·Electroencephalography and Clinical Neurophysiology·F A ECHLIN
Apr 1, 1962·Electroencephalography and Clinical Neurophysiology·S K SHARPLESS, L M HALPERN
Aug 1, 1963·Archives of Neurology·F A ECHLIN, A BATTISTA
Feb 1, 1952·Electroencephalography and Clinical Neurophysiology·C E HENRY, W B SCOVILLE
Aug 1, 1949·Electroencephalography and Clinical Neurophysiology·K KRISTIANSEN, G COURTOIS

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Citations

Sep 19, 1998·Electroencephalography and Clinical Neurophysiology·V DiekmannK H Wollinsky
Sep 19, 1998·Electroencephalography and Clinical Neurophysiology·R WennbergT Rasmussen
Feb 5, 2011·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Richard WennbergDouglas Cheyne
Nov 12, 2013·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Richard Wennberg, Douglas Cheyne
Nov 12, 2013·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Richard Wennberg, Douglas Cheyne
Aug 15, 2009·Seizure : the Journal of the British Epilepsy Association·L Morales ChacónL Rocha Arrieta
Jan 8, 2015·Frontiers in Systems Neuroscience·Jonathan D KennyKen Solt
Aug 5, 2000·The Journal of Thoracic and Cardiovascular Surgery·V AnttilaT Juvonen
Oct 20, 2006·Epilepsy & Behavior : E&B·Tobias LoddenkemperHarold H Morris
Oct 13, 2006·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Dominik ZumstegRichard A Wennberg
May 13, 1999·Anesthesia and Analgesia·P H ManninenH El Beheiry
Jun 1, 2000·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·D B MacDonald, N Pillay
May 31, 2001·Epilepsia·R A Wennberg, L F Quesney

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