PMID: 36176Mar 1, 1979

Induction of ion transport coupled to oxidative reactions in the membranes of mitochondria and liposomes

Biofizika
V T KostavaIu V Evtodienko

Abstract

The mechanism of induction of potassium permeability for mitochondrial membranes under special conditions was under study. Conditions were such as: 1--incubation of mitochondria in medium with low meaning of pH (6,0--6,5), 2--incubation in preseace of electrophylic agent--p-(N,N-di-2-chloroethyl) aminophenylacetic acid, which is hydrolized to HCl and 3-lipidsoluble acid, 2,4-dinitrophenol. It is shown that the named mechanism in any case requires the oxidation of lipids of mitochondrial membranes.

Related Concepts

Dinitrophenols
Nitrogen Mustard Compounds
Tissue Membrane
2,4-Dinitrophenol
Potassium
Mitochondrial Membranes
Mitochondria, Liver
Oxidation
Edetic Acid, Sodium Salt
Mitochondria

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