PMID: 619341Jan 1, 1978

Induction of labor in the high-risk pregnancy with PGF 2 alpha

Obstetrics and Gynecology
M J O'SullivanM L Stephens


The induction of labor in the high-risk patient is accompanied by an increased incidence of cesarean section partly due to failed induction. A series of 50 high-risk patients induced with intravenous prostaglandin F 2 alpha is presented. Forty-five were successfully induced, 35 of whom delivered vaginally. Failed inductions occurred in 5 patients. The overall success rate was 90%, and cesarean section rate was 25.5%. There was an increased incidence of late decelerations in the PGF 2 alpha groups as compared to spontaneous and Pitocin-stimulated labors. While the success was high, the use of a drug which itself may caused fetal cardiovascular changes is not desirable, especially in those pregnancies already at risk.

Related Concepts

Postcesarean Section
Fetal Heart
Induction of Labor Procedure
Prostaglandins F

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