Induction of labor with misoprostol in pregnancies with advanced maternal age

European Journal of Obstetrics, Gynecology, and Reproductive Biology
Sahin ZeterogluHuseyin Avni Sahin

Abstract

The objective was to compare the efficacy and complications of intravaginal misoprostol application with oxytocin infusion for induction of labor in advanced aged pregnancies with a Bishop score of < 6. A hundred advanced aged (> or = 35 years) pregnant patients with a Bishop score of < 6 were randomized into two groups. The first group (50 patients) received 50 microg intravaginal misoprostol four times with 4 h intervals and the second group received oxytocin infusion for induction of labor starting from 2 mIU/min and was increased every 30 min with 2 mIU/min increments up to a maximum of 40 mIU/min. The time from induction to delivery, the route of delivery, fetal outcome, and maternal complications were recorded. Statistical analyses were performed using the Mann-Whitney U, Chi-squared and t tests to determine differences between the two groups. A p value < or = 0.05 was considered significant. Misoprostol was superior for induction of labor in advanced aged pregnancies with Bishop score of < 6, as the mean time from induction to delivery was 9.61 +/- 4.12 h and 11.46 +/- 4.86 h in the misoprostol and oxytocin groups respectively, with a significant difference between the groups (p = 0.04). The rate of vaginal delivery was ...Continue Reading

References

Jun 1, 1995·American Journal of Obstetrics and Gynecology·R A Bobrowski, S F Bottoms
May 1, 1997·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·F Escudero, H Contreras
Aug 24, 1999·American Journal of Obstetrics and Gynecology·D A Wing
Nov 16, 1999·American Journal of Obstetrics and Gynecology·D AbramoviciB M Sibai
Apr 20, 2001·European Journal of Obstetrics, Gynecology, and Reproductive Biology·N VitoratosG Creatsas
Oct 30, 2004·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·A O IlesanmiA Arowojolu

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Citations

May 17, 2014·International Journal of Food Sciences and Nutrition·Amanda Bagolin do NascimentoEvanilda Teixeira
Nov 8, 2012·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Alessandro FavilliSandro Gerli
Oct 12, 2010·The Cochrane Database of Systematic Reviews·G Justus HofmeyrCynthia Pileggi

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