Induction of labour: a randomised clinical trial of amniotomy versus amniotomy with oxytocin infusion

British Journal of Obstetrics and Gynaecology
P G Moldin, G Sundell

Abstract

To compare two methods of induction of labour-amniotomy with oxytocin infusion versus amniotomy alone. Prospective randomised clinical trial. The department of obstetrics in a Swedish central hospital. One hundred and ninety-six pregnant women with indication for induction of labour at term and a favourable cervix (modified Bishop score > or = 6). The women were randomised to amniotomy followed by oxytocin infusion after 1 h (group A, n = 98) or amniotomy alone (group B, n = 98). If labour had not ensued on the following morning, after approximately 24 h, the women in group B were given an oxytocin infusion. Induction-delivery interval, duration of labour, time spent in delivery ward, oxytocin use, maternal and neonatal clinical outcome. Amniotomy combined with early oxytocin infusion resulted in shorter induction-delivery interval (median 6.0 h; 95% confidence interval (CI) 5.0 to 6.5 h) than amniotomy alone (median 9.0 h; 95% CI 7.5 to 10.0 h). This was due to a shorter latent period in the former group (median 2.3 h; 95% CI 2.0 to 3.0 h) compared to the latter (median 4.3 h; 95% CI 3.0 to 5.5 h). The duration of labour stages 1 and 2 were similar in both groups. The time spent in the delivery ward was slightly reduced for wo...Continue Reading

References

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Citations

Nov 5, 1997·Clinical Obstetrics and Gynecology·D W Laube
Jan 24, 2007·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·R A KhanO Ashraf
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Sep 3, 2021·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·UNKNOWN Writing group:Michel Dreyfus

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