PMID: 6990202Feb 1, 1980Paper

Induction of mutations in specific genes of bacteriophage T4 using cloned restriction fragments and marker rescue

Molecular & General Genetics : MGG
T A Völker, M K Showe

Abstract

Saturation of a specific region of a chromosome with conditional lethal mutations becomes increasingly difficult as the genome size of the organism increases. We show that mutagenesis of cloned genes followed by their re-integration into a non-mutagenized organism is a practical way to circumvent this difficulty.

References

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Citations

Oct 25, 1981·Journal of Molecular Biology·D B OliverE B Goldberg
Jan 25, 1982·Journal of Molecular Biology·T A VölkerT A Bickle
Feb 15, 1991·Proceedings of the National Academy of Sciences of the United States of America·V L WatersD G Guiney
May 25, 1983·Journal of Molecular Biology·R A Driedonks, J Caldentey
Sep 23, 1982·Nature·A C Christensen, E T Young
May 14, 2021·Frontiers in Microbiology·Luis Ramirez-ChamorroOmbeline Rossier
Mar 1, 1984·Journal of Virology·F Traub, M Maeder
Jun 1, 1992·Journal of Bacteriology·P G AgronD R Helinski
Sep 1, 1982·Mutation Research·T Gichner, J Velemínský
Nov 15, 1981·Journal of Molecular Biology·R A Driedonks van Driel

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