PMID: 2158902Apr 9, 1990Paper

Induction of normal ultrastructure by CGRP treatment in dysgenic myotubes

FEBS Letters
L GarciaF Rieger

Abstract

The calcitonin gene-related peptide (CGRP) restores an apparent normal ultrastructure in mdg/mdg muscle cells in vitro, including a normal triadic organization which is known to be essential for excitation-contraction (E-C) coupling. However, neither slow L-type Ca2+ channel activity nor E-C coupling, which are absent in mdg/mdg muscle, were re-established. These observations suggest a potential role of CGRP (and also of cAMP as the intracellular messenger) in the morphological development of the muscle fiber.

References

Jan 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·L HymelH Schindler
Aug 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·C MulleJ P Changeux
Apr 1, 1989·Proceedings of the National Academy of Sciences of the United States of America·G RomeyM Lazdunski
Jan 1, 1986·Progress in Brain Research·T HökfeltL Olson
Nov 1, 1967·Journal of Biochemistry·T MasakiS Ebashi
Mar 1, 1972·Developmental Biology·F Bowden-Essien
Aug 1, 1981·Pflügers Archiv : European journal of physiology·O P HamillF J Sigworth
Dec 6, 1963·Science·S GLUECKSOHN-WAELSCH

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Citations

Mar 1, 1991·Pflügers Archiv : European journal of physiology·M GrouselleD Georgescauld
Aug 1, 1991·Developmental Biology·C Franzini-ArmstrongF Rieger
Apr 29, 1998·Progress in Neurobiology·M Akinori
Jun 30, 1992·Annals of the New York Academy of Sciences·J P ChangeuxS Sekine
Feb 1, 1995·Developmental Dynamics : an Official Publication of the American Association of Anatomists·M BretonL Garcia

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