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Induction of Noxa-mediated apoptosis by modified vaccinia virus Ankara depends on viral recognition by cytosolic helicases, leading to IRF-3/IFN-β-dependent induction of pro-apoptotic Noxa

PLoS Pathogens

Jun 24, 2011

Pedro Eitz FerrerGeorg Häcker

Abstract

Viral infection is a stimulus for apoptosis, and in order to sustain viral replication many viruses are known to carry genes encoding apoptosis inhibitors. F1L, encoded by the orthopoxvirus modified vaccinia virus Ankara (MVA) has a Bcl-2-like structure. An MVA mutant lacking F1L (MVAΔF...read more

Mentioned in this Paper

CD19 gene
CREB1 gene
HOXB8 gene
MARCKS gene
MYD88 gene
PPAT gene
BBC3 gene
CYCS gene
COASY gene
Amidophosphoribosyltransferase
Paper Details
References
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Induction of Noxa-mediated apoptosis by modified vaccinia virus Ankara depends on viral recognition by cytosolic helicases, leading to IRF-3/IFN-β-dependent induction of pro-apoptotic Noxa

PLoS Pathogens

Jun 24, 2011

Pedro Eitz FerrerGeorg Häcker

PMID: 21698224

DOI: 10.1371/journal.ppat.1002083

Abstract

Viral infection is a stimulus for apoptosis, and in order to sustain viral replication many viruses are known to carry genes encoding apoptosis inhibitors. F1L, encoded by the orthopoxvirus modified vaccinia virus Ankara (MVA) has a Bcl-2-like structure. An MVA mutant lacking F1L (MVAΔF...read more

Mentioned in this Paper

CD19 gene
CREB1 gene
HOXB8 gene
MARCKS gene
MYD88 gene
PPAT gene
BBC3 gene
CYCS gene
COASY gene
Amidophosphoribosyltransferase

Similar Papers Found In These Feeds

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Paper Details
References
  • References49
  • Citations22
12345
  • References49
  • Citations22
123
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