Induction of polymorphic ventricular tachycardia by programmed ventricular stimulation in vasospastic angina pectoris

The American Journal of Cardiology
Mitsuhiro NishizakiMasayasu Hiraoka

Abstract

This study was designed to examine the ventricular vulnerability of patients with vasospastic angina. Fourteen patients (mean age 57 +/- 9 years) with vasospastic angina underwent electrophysiologic testing during the asymptomatic phase (baseline) and after the relief of acetylcholine-induced spasm with isosorbide dinitrates. Twenty patients without structural heart disease served as a control group. By programmed ventricular stimulation, polymorphic ventricular tachycardia (VT) was induced at baseline in 6 of 14 patients, with 1 patient developing ventricular fibrillation and 7 of 14 patients developing repetitive ventricular responses. After isosorbide dinitrate, polymorphic VT was induced in only 1 patient who had ventricular fibrillation at baseline. Repetitive ventricular responses were induced in 3 of 5 patients who had VT at baseline and in 4 of the 7 patients with repetitive ventricular responses at baseline. There was a significant difference in the incidences and severity of induced ventricular arrhythmias between the 2 phases (p <0.01). Among 20 control subjects, repetitive ventricular responses were induced only in 6 patients, but no VT was induced. There was a significant difference in the incidence of induced vent...Continue Reading

References

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Citations

Aug 4, 2012·The American Journal of Cardiology·Hiroshi ShimadaMasayasu Hiraoka
Jun 28, 2011·International Journal of Cardiology·Yae Min ParkEak Kyun Shin
Jun 3, 2009·Heart & Lung : the Journal of Critical Care·Gabor KissCharles Chistian Arvieux
Aug 12, 2009·Journal of Hospital Medicine : an Official Publication of the Society of Hospital Medicine·Pradeep K Bhat, Kara J Quan
Oct 8, 1999·The American Journal of Cardiology·T AshikagaM Hiraoka
Oct 19, 2006·International Journal of Cardiology·Konstantinos P LetsasFotios Kardaras
Jul 28, 2016·Hellenic Journal of Cardiology : HJC = Hellēnikē Kardiologikē Epitheōrēsē·Kali PolytarchouAntonis S Manolis
Oct 9, 2002·Journal of Internal Medicine·W SeniukA Cieśliński
Mar 10, 2018·Current Cardiology Reports·Amartya KunduNaomi F Botkin
Aug 26, 1998·Circulation·M SuzukiM Hiraoka
Dec 20, 2017·Journal of Arrhythmia·Mitsuhiro Nishizaki
Jan 30, 2008·European Journal of Anaesthesiology·G KissC C Arvieux

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