PMID: 7019681Nov 1, 1980Paper

Induction of spontaneous and UV-induced mutations during commitment to meiosis in Saccharomyces cerevisiae

Mutation Research
I Machida, S Nakai

Abstract

Inductions of reversions of nonsense, missense and frameshift-type mutations were investigated in a diploid cell population of Saccharomyces cerevisiae during commitment to meiosis, by using the medium-transfer technique from sporulation medium to vegetative medium. The yields of spontaneous reverse mutations obtained from the cells that were committed to different stages during meiosis were rather constant irrespective of the alleles tested, although the yields of both intergenic and intragenic recombinations markedly increased. The susceptibilities to UV-induced reverse mutations examined during commitment to meiosis were not changed appreciably. It is concluded that induction of base-change-type mutations in meiosis is not essentially different from that in mitosis.

References

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Citations

Jun 1, 1989·Molecular & General Genetics : MGG·H H de AndradeJ A Henriques
Sep 1, 1990·Mutation Research·G von PoserJ A Henriques
Jul 1, 1985·Mutation Research·N J Sargentini, K C Smith
May 13, 2006·Biometals : an International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine·C ViauM Brendel
Jun 2, 2005·Mutation Research·C PungartnikM Brendel
Jan 8, 2008·Mutation Research·Luis Fernando da Costa MedinaJoão Antonio Pêgas Henriques
Oct 1, 1989·Molecular & General Genetics : MGG·H H de AndradeJ A Henriques
Sep 15, 2004·Mutation Research·Renato Moreira RosaJoão Antonio Pêgas Henriques

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