PMID: 9550594Apr 29, 1998Paper

Induction of torsades de pointes by dobutamine infusion in a patient with idiopathic long QT syndrome

Internal Medicine
H FujikawaK Shimada

Abstract

We used a provocative test with dobutamine infusion to diagnose long QT syndrome (LQTS) in a girl with a history of syncope. When dobutamine was infused at a rate of 10 microg/kg/min, the QT interval corrected for heart rate (QTc) was prolonged from 460 ms to 620 ms with abnormal TU complexes and torsades de pointes developed. In 5 control subjects the QTc did not change significantly during low-dose dobutamine infusion. Low-dose dobutamine, in addition to isoproterenol, may be useful for evaluation of prolongation of the QT interval and abnormal TU complexes in patients in whom LQTS is suspected.

Citations

Dec 2, 2008·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Ilias KarabinosDemosthenes Katritsis
Dec 3, 2005·International Journal of Cardiology·Jürg SchläpferEtienne Pruvot
Feb 5, 2005·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Rashmi R Shah
Jan 27, 2021·Journal of Cardiothoracic and Vascular Anesthesia·Naoko NiimiKatherine Zaleski

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