Abstract
A cDNA clone encoding tyrosine hydroxylase (TH) was isolated from larval fat body of immunized Samia cynthia ricini. In naive larvae, the TH gene was expressed only in the brain, but strongly induced in fat body and hemocytes after injecting UV-killed bacteria. The induction of the gene was rather short-lived compared to that of antibacterial protein genes, reaching the maximum levels 6h after bacterial challenge, and then quickly diminished. A strong induction of the gene expression was caused by both Gram-negative and positive bacteria and zymosan, but little if any by soluble peptidoglycan or lipopolysaccharide. A possible role of TH in the fat body of bacteria-challenged larvae would be to supply catecholamines as the substrate for phenoloxidase leading to melanization, working together with dopa decarboxylase.
References
Dec 31, 1990·Biochemical and Biophysical Research Communications·S IchikawaT Nagatsu
Apr 16, 1987·Nature·B GrimaJ Mallet
Apr 2, 1998·Current Opinion in Immunology·K Söderhäll, L Cerenius
Mar 10, 1999·Insect Biochemistry and Molecular Biology·M IketaniI Morishima
May 20, 1999·Microscopy Research and Technique·M Monastirioti
Sep 3, 1999·Genetics·D G StathakisJ M O'Donnell
Apr 28, 2000·European Journal of Biochemistry·M H KimB L Lee
Apr 6, 2001·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·S FujimotoI Morishima
Oct 19, 2001·Proceedings of the National Academy of Sciences of the United States of America·E De GregorioB Lemaitre
Jul 12, 2002·Insect Biochemistry and Molecular Biology·Keiko KishimotoIsao Morishima
Feb 20, 2003·Developmental and Comparative Immunology·V SeitzL Podsiadlowski
Jun 18, 2004·Immunological Reviews·Vincent Leclerc, Jean-Marc Reichhart
Jun 18, 2004·Immunological Reviews·Michael R KanostXiao-Qiang Yu
Dec 29, 2004·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Yanyuan BaoIsao Morishima
Nov 28, 2006·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Yanyuan BaoIsao Morishima
Apr 17, 2007·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Hiroko OnoeIsao Morishima
Aug 11, 2007·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Kazuhiko HashimotoIsao Morishima
Jul 23, 1982·Science·T L HopkinsK J Kramer
Citations
Jun 30, 2012·Science China. Life Sciences·Wei SunZe Zhang
Sep 9, 2010·Archives of Insect Biochemistry and Physiology·Se Hui HwangYong Chul Park
Jul 16, 2016·Scientific Reports·Liang QiaoBin Chen
Sep 25, 2017·Pest Management Science·Er-Hu ChenJin-Jun Wang