Infant and childhood diet and type 1 diabetes risk: recent advances and prospects.

Current Diabetes Reports
Jill M Norris

Abstract

Type 1 diabetes is a chronic autoimmune disease characterized by a preclinical period of autoimmunity. It is well accepted that both genetic and environmental factors contribute to disease risk. Given that type 1 diabetes, and its preclinical autoimmunity, appear early in life, infant and childhood diet have been implicated as potential initiating exposures in the etiology of the disease. Several publications in the past year have provided further evidence for existing hypotheses regarding the roles of wheat, cow's milk, omega-3 fatty acids, and the maternal diet during pregnancy. However, inconsistencies in findings between studies suggest the need for collaboration and standardization of study methods to move forward in research in this area. One such example of this is the TEDDY (The Environmental Determinants of Diabetes in the Young) study, which is an international, multicenter birth cohort study with standardized recruitment, dietary collection methodologies, and analytic approaches.

References

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Citations

Jan 2, 2013·The Journal of Experimental Medicine·Qibin ZhangThomas O Metz
Jan 31, 2013·Annals of the New York Academy of Sciences·Natalie Nokoff, Marian Rewers
May 10, 2015·Diabetologia·Austin G Davis-Richardson, Eric W Triplett
Apr 18, 2015·BioMed Research International·Yukiko Kagohashi, Hiroki Otani
Jul 15, 2016·Pediatric Diabetes·Suvi M Virtanen
Mar 1, 2020·Scientific Reports·Randi K JohnsonJill M Norris
Sep 10, 2020·Nutrients·Antonio CorselloAlessandro Armuzzi
Aug 25, 2021·JAMA : the Journal of the American Medical Association·Jean M LawrenceUNKNOWN SEARCH for Diabetes in Youth Study Group

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