Infant birthweight in the US: the role of preconception stressful life events and substance use

Archives of Women's Mental Health
Whitney P WittDakota Zarak

Abstract

The purpose of this study was to determine the relationships among preconception stressful life events (PSLEs), women's alcohol and tobacco use before and during pregnancy, and infant birthweight. Data were from the Early Childhood Longitudinal Study-Birth Cohort (n = 9,350). Data were collected in 2001. Exposure to PSLEs was defined by indications of death of a parent, spouse, or previous live born child; divorce or marital separation; or fertility problems prior to conception. Survey data determined alcohol and tobacco usage during the 3 months prior to and in the final 3 months of pregnancy. We used staged multivariable logistic regression to estimate the effects of women's substance use and PSLEs on the risk of having a very low (<1,500 g, VLBW) or low (1,500-2,499 g, LBW) birthweight infant, adjusting for confounders. Women who experienced any PSLE were more likely to give birth to VLBW infants (adjusted odds ratio [AOR] = 1.35; 95 % confidence interval [CI] = 1.10-1.66) than women who did not experience any PSLE. Compared to women who never smoked, women who smoked prior to conception (AOR = 1.31; 95 % CI = 1.04-1.66) or during their last trimester (AOR = 1.98; 95 % CI = 1.56-2.52) were more likely to give birth to LBW in...Continue Reading

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Citations

Jul 21, 2020·Annals of Behavioral Medicine : a Publication of the Society of Behavioral Medicine·N E MahrerC Dunkel Schetter
Dec 5, 2016·Archives of Women's Mental Health·Betty-Shannon PrevattPatricia A Janssen
Dec 19, 2018·Journal of the American Heart Association·Vineeta TanwarLoren E Wold
Jun 6, 2021·Pediatric Research·Kazutoshi ChoUNKNOWN Japan Environment and Children’s Study Group

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