Infant botulism type Ba: first culture-confirmed case in the United Arab Emirates

Pediatric Neurology
Waseem M FathallaElamin Ahmed

Abstract

We report on a 3-month-old girl with culture-confirmed infant botulism caused by a rare double toxin-producing Clostridium botulinum type Ba. This case was not related to honey-feeding. The clinical course was prolonged, with minimal spontaneous improvement at onset, and a period of fluctuating motor weakness and nasogastric feeding dependence afterward. Neurophysiologic studies produced normal results. Human botulism immune globulin was administered empirically on day 23 of presentation, with rapid full recovery. This case highlights the importance of pursuing diagnoses of infant botulism despite normal results of neurophysiologic testing and no history of honey-feeding. Our case also demonstrates a favorable response to human botulism immune globulin, despite the relatively late treatment.

References

Feb 1, 1979·The Journal of Pediatrics·S S ArnonJ Chin
Dec 1, 1979·The Journal of Pediatrics·C L'HommedieuR Polin
Jul 1, 1983·Muscle & Nerve·D R CornblathA J Sumner
Feb 26, 2005·Pediatric Neurology·Christine K FoxJonathan B Strober
Oct 19, 2006·Medical Principles and Practice : International Journal of the Kuwait University, Health Science Centre·Maria M J van der VorstAlie Moosa
Apr 4, 2007·Pediatrics·Ann Marie O Francisco, Stephen S Arnon

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Citations

Nov 7, 2012·Journal of Food Protection·Rabih KamlehBassam A Annous

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Botulism (ASM)

Botulism is a rare but serious paralytic illness caused by a nerve toxin that is produced by the bacterium clostridium botulinum. Discover the latest research on botulism here.

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Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.

Aminoglycosides

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.

Botulism

Botulism is a rare but serious paralytic illness caused by a nerve toxin that is produced by the bacterium clostridium botulinum. Discover the latest research on botulism here.

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