Infant dietary patterns and bone mass in childhood: the Generation R Study

Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
Edith H van den HoovenO H Franco

Abstract

Early life nutrition affects peak bone mass attainment. In this prospective cohort study, children with high adherence to a "dairy and whole grains" pattern in infancy had higher bone mineral density at the age of 6 years. Although the observed effects are small, our study provides insight into mechanisms linking early nutrition to bone acquisition in childhood. Nutrition in early life may affect peak bone mass attainment. Previous studies on childhood nutrition and skeletal health mainly focused on individual nutrients, which does not consider the cumulative effects of nutrients. We investigated the associations between dietary patterns in infancy and childhood bone health. This study included 2850 children participating in a population-based prospective cohort study. Dietary information was obtained from a food frequency questionnaire at the age of 13 months. Using principal component analysis, three major dietary patterns were extracted, explaining in total 30% of the variation in dietary intake. At the age of 6 years, a total body dual-energy X-ray absorptiometry (DXA) scan was performed, and bone mineral density (BMD), bone mineral content (BMC), area-adjusted BMC (aBMC), and bone area (BA) were analyzed. Higher adherence ...Continue Reading

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Citations

Feb 10, 2016·The British Journal of Nutrition·Edith H van den HoovenVincent W V Jaddoe
Sep 29, 2015·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·P J MitchellR Rizzoli
Sep 18, 2015·The American Journal of Clinical Nutrition·Edith H van den HoovenWendy H Oddy
Nov 8, 2018·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Teresa MonjardinoRaquel Lucas
Jan 10, 2019·The American Journal of Clinical Nutrition·Julie E ObbagyEve E Stoody
Jan 31, 2019·Public Health Nutrition·Sarah Aparecida VieiraSylvia do Carmo Castro Franceschini
Jun 1, 2019·Journal of Pediatric Endocrinology & Metabolism : JPEM·Yali RenYukai Du
Sep 15, 2020·Critical Reviews in Food Science and Nutrition·Taylor C WallaceConnie M Weaver
Feb 12, 2021·Current Osteoporosis Reports·Lauren M Coheley, Richard D Lewis
Oct 17, 2017·The Journal of Pediatrics·Teresa MonjardinoRaquel Lucas

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Methods Mentioned

BETA
X-ray
PCA

Software Mentioned

SPSS

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