PMID: 2060453May 1, 1991

Infant feeding in Finnish children less than 7 yr of age with newly diagnosed IDDM. Childhood Diabetes in Finland Study Group

Diabetes Care
S M VirtanenH K Akerblom


We studied associations between the type of feeding in infancy and the incidence of insulin-dependent diabetes mellitus (IDDM). We studied 103 newly diagnosed diabetic children less than 7 yr of age and 103 age- and sex-matched population-based control children in a countrywide study. The risk of IDDM was decreased (P less than 0.05) among children breast-fed for at least 7 mo (odds ratio [OR] 0.45, 95% confidence interval [CI] 0.24-0.85) or exclusively breast-fed for at least 3 (OR 0.33, 95% CI 0.13-0.84) or 4 (OR 0.43, 95% CI 0.22-0.84) mo. Also, children who were greater than or equal to 4 mo old at the time of introduction of supplementary milk feeding had a lower risk of diabetes (OR 0.48, 95% CI 0.26-0.91). The protective effects of a long duration of breast-feeding and a late introduction of dairy products on the risk of IDDM remained significant after adjusting for the mother's education.


Apr 4, 2001·Indian Journal of Pediatrics·F EsfarjaniM Gafarpour
Jan 1, 1995·Molecular Aspects of Medicine·W J KargesH M Dosch
Jan 30, 1999·Diabetes Research and Clinical Practice·T Y TaiC J Chen
Oct 6, 1997·Endocrinology and Metabolism Clinics of North America·J S Skyler
Jan 19, 1999·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·L A Hanson
Oct 10, 1998·Journal of Paediatrics and Child Health
Apr 12, 2000·Journal of Paediatrics and Child Health·K Simmer
Jul 30, 1992·The New England Journal of Medicine·J KarjalainenH M Dosch
Nov 26, 1992·The New England Journal of Medicine·E W Chideckel
Dec 16, 1993·The New England Journal of Medicine·M A AtkinsonN K Maclaren
Nov 12, 2010·The New England Journal of Medicine·M KnipFinnish TRIGR Study Group
Dec 16, 1998·The British Journal of Nutrition·B KoletzkoS Strobel
Sep 24, 2005·The British Journal of Nutrition·Hilde K BrekkeJohnny Ludvigsson
Apr 12, 2000·Journal of the American College of Nutrition·J Schrezenmeir, A Jagla
Mar 5, 2003·Diabetes Technology & Therapeutics·William E WinterDesmond Schatz
Jul 5, 2012·Cold Spring Harbor Perspectives in Medicine·M Knip, O Simell
Dec 1, 1994·Scandinavian Journal of Immunology·R CheungH M Dosch
Apr 1, 1992·Diabetic Medicine : a Journal of the British Diabetic Association·K O KyvikK Mortensen
Nov 1, 1992·Diabetic Medicine : a Journal of the British Diabetic Association·S M VirtanenH K Akerblom
May 1, 1997·Acta Paediatrica. Supplement·K F Michaelsen
Jan 30, 1993·BMJ : British Medical Journal·T J Wilkin
Oct 1, 1993·The Journal of Clinical Investigation·M A Atkinson, N K Maclaren
Aug 8, 2012·International Journal of Women's Health·Satoko Ebina, Ikuo Kashiwakura
Apr 14, 2009·American Journal of Epidemiology·Thomas HarderAndreas Plagemann
Dec 1, 1994·Annals of Medicine·S M Virtanen, A Aro
Oct 1, 1991·Annals of Medicine·H K Akerblom, M Knip
Aug 12, 2015·The American Journal of Gastroenterology·Benjamin LebwohlChaitan Khosla
Aug 20, 2004·Diabetic Medicine : a Journal of the British Diabetic Association·A L MarshallD Thistlethwaite
Aug 25, 2004·Perspectives in Psychiatric Care·Kirsten MaloneNorman L Keltner
Dec 8, 2006·Annals of the New York Academy of Sciences·Ernest AdeghateEarl Dunn

Related Concepts

Diabetes Mellitus, Insulin-Dependent
Diabetes, Autoimmune
Breast Feeding, Exclusive
Infant Food
Infant Nutrition

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