Infantile Cytomegalovirus-Associated Severe Warm Autoimmune Hemolytic Anemia: A Case Report

Children
Hassan K KhalifehCynthia T Chamoun

Abstract

Autoimmune hemolytic anemia is a rare hematologic entity in children. Etiologies are mainly viruses or bacteria. We describe here a case of severe warm autoimmune hemolytic anemia (IgG- and C3d-positive direct antiglobulin test) in an immunocompetent 6-month-old infant with acute Cytomegalovirus infection that responded well to corticotherapy and intraveneous immunoglobulins without using blood component transfusion. This case demonstrates the importance of recognizing CMV in infantile Autoimmune Hemolytic Anemia, especially because hemolysis can be severe and lethal.

References

Apr 22, 1983·JAMA : the Journal of the American Medical Association·Y S AhnJ McCrainie
Jul 24, 2001·Journal of Pediatric Hematology/oncology·J C MurrayA B Morad
Jul 2, 2002·Blood·Victor M MoyoRobert A Brodsky
Jul 14, 2005·Journal of Pediatric Hematology/oncology·David T Teachey, Carolyn A Felix
Jul 7, 2007·Pediatric Hematology and Oncology·Rahul NaithaniV P Choudhry
Mar 29, 2008·Virology Journal·Petros I RafailidisMatthew E Falagas
Jan 14, 2011·Haematologica·Nathalie AladjidiUNKNOWN Centre de Référence National des Cytopénies Auto-immunes de l'Enfant (CEREVANCE)
Aug 11, 2011·Infectious Disorders Drug Targets·Mark R Schleiss
Jan 5, 2014·The Ceylon Medical Journal·D Gunawardena, G A Gamakaranage
Feb 24, 2015·BioMed Research International·Sigbjørn Berentsen, Tatjana Sundic
Dec 24, 2015·Transfusion Medicine and Hemotherapy : Offizielles Organ Der Deutschen Gesellschaft Fur̈ Transfusionsmedizin Und Immunham̈atologie·Wilma Barcellini
Dec 24, 2015·Transfusion Medicine and Hemotherapy : Offizielles Organ Der Deutschen Gesellschaft Fur̈ Transfusionsmedizin Und Immunham̈atologie·Charles H Packman

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Citations

May 3, 2019·Pediatric Blood & Cancer·Bruno LoureiroPaula Kjöllerström
Sep 26, 2020·Anales de pediatría : publicación oficial de la Asociación Española de Pediatría (A.E.P.)·Nazaret SánchezJulián Sevilla
May 26, 2021·Neonatology·Shunsuke YamamotoShouichi Ohga

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Methods Mentioned

BETA
PCR

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Autoimmune Hemolytic Anemia

Autoimmune hemolytic anemia (AIHA) occurs when antibodies directed against the person's own red blood cells (RBCs) cause them to burst (lyse), leading to an insufficient number of oxygen-carrying red blood cells in the circulation. Discover the latest research on AIHA here.

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