Infantile-onset cutaneous T-cell lymphoma

The British Journal of Dermatology
A TsianakasP H Hoeger

Abstract

Mycosis fungoides (MF), the most common form of cutaneous T-cell lymphoma (CTCL), is mainly a disease of the elderly. To review paediatric CTCL cases reported in the literature, with a focus on the time between onset of symptoms and establishment of a correct diagnosis. A review of the literature was carried out and a case reported. A total of 254 cases of CTCL have been reported in children aged<16 years, 13 cases (<1% of all reported cases) in children below the age of 2 years, and only seven cases (including ours) during the first year of life. CTCL was most prevalent in children aged 10-12 years. The delay between age of onset and establishment of diagnosis was largest in the youngest age group (0-3 years), and declined steadily thereafter, thus reflecting the increasing likelihood that CTCL is considered in the differential diagnosis of skin disorders with increasing age of the patient. The diagnosis of CTCL is frequently delayed in young children. It needs to be considered in chronic 'eczematous' skin lesions irrespective of the patient's age, and including infants.

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Citations

Jun 9, 2009·Current Opinion in Pediatrics·John C Browning
Dec 3, 2014·Journal of Cutaneous Pathology·Heiko PoppeHenning Hamm
Nov 18, 2009·Annales de dermatologie et de vénéréologie·J Di Lucca-ChrismentB Crickx
Dec 11, 2013·Journal of Cutaneous Pathology·Ekaterina CastanoMark Jacobson
Jun 12, 2014·Pediatric Dermatology·Philip M LawsElena Pope
Apr 7, 2016·JAAD Case Reports·Judy K QiangJensen Yeung
Nov 6, 2009·Current Opinion in Supportive and Palliative Care
Jul 7, 2019·Actas dermo-sifiliográficas·O J Valencia OcampoM M Velásquez-Lopera
Jan 4, 2022·Journal of Palliative Medicine·Jennifer A SalantAnjali V Desai

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