PMID: 7513419Mar 1, 1994Paper

Infantile systemic hyalinosis in a black infant

Pediatric Dermatology
E E SahnK A Holbrook

Abstract

A black girl was born with flexion contractures and experienced pain on movement by 1 week of age. She subsequently developed perioral papules, gingival hyperplasia, perianal nodules, torticollis, diarrhea, rectal prolapse, and inability to open her mouth. Her skin became increasingly sclerodermatous, and velvety, hyperpigmented plaques arose over bony prominences. A skin biopsy specimen showed hyaline material in the papillary dermis with lack of elastic fibers. Ultrastructural examination revealed fibrillogranular material around fibroblasts and blood vessels. This child had the clinical, histologic, and ultrastructural features of infantile systemic hyalinosis. This disorder has not been described in a black infant. Previous case reports of infantile systemic hyalinosis are reviewed and unusual features of our case are discussed.

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Citations

Dec 6, 2005·Clinical Rheumatology·Yahya AghighiLaleh Razavi Nematollahi
Jan 17, 2004·Journal of the American Academy of Dermatology·Helen T ShinSeth J Orlow
Aug 13, 1998·The American Journal of Dermatopathology·B C WinikR Asial
Oct 1, 1996·International Journal of Dermatology·W K Jacyk, L F Wentzel
May 11, 2012·Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society·Cheryl M Coffin, Rita Alaggio
Jul 1, 2010·Indian Dermatology Online Journal·Bhushan MadkeUday Khopkar
Aug 25, 2004·American Journal of Medical Genetics. Part a·Germán Rodríguez CriadoIgnacio Gómez De Terreros
Jan 29, 2008·Journal of the American Academy of Dermatology·Lisa E LindvallSenait W Dyson
Sep 6, 2002·American Journal of Human Genetics·Nazneen RahmanF Michael Pope
Jul 7, 2001·Acta Paediatrica·C Thauvin-RobinetF Huer
Apr 14, 2004·Pediatric Dermatology·Francisco UrbinaGuillermo Murray
Feb 18, 2016·The American Journal of Dermatopathology·Maral RahvarJinah Kim
Sep 23, 2003·The Journal of Craniofacial Surgery·Imad Al-NajjadahJames R Kanjoor

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