Infection does not cause reflux

AJR. American Journal of Roentgenology
G W Gross, R L Lebowitz

Abstract

Vesicoureteric reflux in children was originally considered to be a secondary phenomenon, caused by distal obstruction. We now know, however, that most children with vesicoureteric reflux are not obstructed. More recently, urinary tract infection has been thought to be the cause of most vesicoureteric reflux. To test this hypothesis, the results of 601 voiding cystourethrograms with simultaneous culture of the urine (in children), over a 12 month period were analyzed. Of the 34% (204/601) with vesicoureteric reflux, 88% (179/204) had sterile urine and 12% (25/204) were infected. Of the 66% (397/601) without reflux, 90% (357/397) had sterile and 10% (40/397) infected urine. These data do not support the concept that vesicoureteric reflux is secondary to infection in these children. On the contrary, it suggests that reflux and urinary tract infection are independent variables that often coexist. It is concluded that vesicoureteric reflux is a primary phenomenon and is due to incompetence of the ureterovesical junction.

Citations

Oct 1, 1987·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·H Olbing
Jan 1, 1988·Pediatric Radiology·P A Nancarrow, R L Lebowitz
Jan 1, 1983·Urologic Radiology·U Willi, S Treves
Jan 1, 1983·Urologic Radiology·J A Roberts
Jan 1, 1985·Urologic Radiology·E J Urrutia, R L Lebowitz
Feb 1, 1993·Australasian Radiology·M R Ditchfield, J F de Campo
Oct 1, 2007·Indian Journal of Urology : IJU : Journal of the Urological Society of India·Sumit Dave, Antoine E Khoury
Sep 18, 2002·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Teresa BerrocalJulia Gutiérrez
Jan 1, 1994·Neurourology and Urodynamics·G M GhoniemJ A Roberts
Feb 1, 1993·Community Dentistry and Oral Epidemiology·M GonzálezA Aguirre
Apr 14, 2012·Radiologic Clinics of North America·Puneet BhargavaCarolyn Wang
Dec 1, 1999·Pediatric Annals·D J Pennington, J M Zerin
Sep 9, 2008·Journal of Pediatric Urology·Marc Cendron
Jul 28, 2006·Annales D'urologie·D DemèdeP Mouriquand
Nov 5, 1997·Pediatric Clinics of North America·H G Rushton
Jan 1, 1985·Acta Radiologica: Diagnosis·H S Thomsen
Sep 13, 2003·Ultrasound Quarterly·Harriet J Paltiel
Sep 9, 2017·Disease Models & Mechanisms·Patrick D OlsonDavid A Hunstad
Feb 1, 1982·The Journal of Urology·J W Duckett
Jan 1, 1986·Acta Medica Scandinavica. Supplementum·S H Jacobson
Dec 24, 1997·Journal of Paediatrics and Child Health·J C CraigL P Roy
Jul 1, 1988·The Journal of Urology·A B PintérI Dóber
Dec 10, 1999·Acta Paediatrica. Supplement·M Hellström, B Jacobsson
Jun 1, 1983·The Journal of Urology·J A Roberts
Oct 1, 1988·Seminars in Nuclear Medicine·J J Conway

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.