PMID: 8513644Mar 1, 1993

Infection due to Chlamydia trachomatis in pregnancy and the newborn

Baillière's Clinical Obstetrics and Gynaecology
J R Smith, D Taylor-Robinson

Abstract

Bacteria in the genus Chlamydia comprise three species, C. trachomatis, C. psittaci and C. pneumoniae. C. trachomatis infection is common, varying in prevalence in women from 0% to 37%. In the United States, the prevalence rate is estimated currently to be about 5%. Pregnancy may predispose to an increased chance of infection with C. trachomatis, through physiological immunosuppression and/or cervical ectopy. Maternal antibodies to C. trachomatis provide limited, if any, protection for the newborn. C. trachomatis causes pelvic inflammatory disease--which can result in tubal infertility or ectopic pregnancy and postabortal or late postpartum endometritis. It may also cause chorioamnionitis and premature delivery of the fetus. The incidence of vertical transmission of chlamydiae from mother to baby varies; if the mother is untreated, 20-50% of the newborns will develop conjunctivitis and 10-20% will develop pneumonia. C. psittaci infection in pregnancy is rare, but can cause spontaneous abortion. Whether C. pneumoniae infection in pregnancy has any influence on the outcome has not been ascertained. C. trachomatis can be detected by one or more of several methods; enzyme immunoassays are the least sensitive, but the most widely us...Continue Reading

References

Aug 25, 1979·Lancet·J SchachterJ Mills
Jul 1, 1979·The Journal of Pediatrics·G T FrommellK McIntosh
Dec 1, 1979·The Journal of Infectious Diseases·H R Harrison, R T Riggin
Nov 1, 1975·The Journal of Pediatrics·J SchachterB Ostler
Aug 1, 1991·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·B J ThomasD Taylor-Robinson
Dec 1, 1991·British Journal of Obstetrics and Gynaecology·Y VilleM Ward
Jan 12, 1991·BMJ : British Medical Journal·J R SmithJ A Davis
Jun 1, 1991·American Journal of Obstetrics and Gynecology·W Cates, J N Wasserheit
Jun 1, 1991·Genitourinary Medicine·D Taylor-Robinson, B J Thomas
Jul 1, 1990·Sexually Transmitted Diseases·K J ShermanJ T Grayston
Oct 1, 1990·Sexually Transmitted Diseases·A M Goldstein, J H Clark
May 1, 1990·Obstetrics and Gynecology·W R CrombleholmeR Sweet
Nov 1, 1989·American Journal of Obstetrics and Gynecology·R J BiggarJ J Goedert
Apr 1, 1989·European Journal of Obstetrics, Gynecology, and Reproductive Biology·A N FishG L Ridgway
Jan 1, 1989·Sexually Transmitted Diseases·A EstanyR McLaren
Aug 22, 1987·Lancet·D C MabeyJ D Treharne
Mar 23, 1989·The New England Journal of Medicine·M R HammerschlagI Delke
Jan 1, 1988·Journal of Medical Microbiology·M TuffreyD Taylor-Robinson
Oct 1, 1988·Epidemiology and Infection·D Hobson, P Morgan-Capner
Apr 4, 1986·JAMA : the Journal of the American Medical Association·H H HandsfieldW E Stamm
Oct 13, 1988·The New England Journal of Medicine·Sharon L HillierDavid A Eschenbach
Jan 1, 1988·American Journal of Obstetrics and Gynecology·G B ThomasR J Selvaraj
Jan 30, 1986·The New England Journal of Medicine·J SchachterE Bishop
Jul 1, 1986·Pediatric Infectious Disease·P J Rettig
Jun 1, 1987·Genitourinary Medicine·E FrostA Meheus
Jan 1, 1987·Acta Obstetricia Et Gynecologica Scandinavica·G GiertzT Fuchs
May 1, 1986·The Journal of Pediatrics·S G WeissM O Beem
Jun 27, 1986·JAMA : the Journal of the American Medical Association·J SchachterE Bishop
Sep 1, 1986·Journal of Reproduction and Fertility·M TuffreyD Taylor-Robinson
Feb 23, 1985·British Medical Journal·F W JohnsonK M Hadley
Feb 1, 1985·American Journal of Diseases of Children·C SchaeferM Lewis
Jun 1, 1985·American Journal of Obstetrics and Gynecology·J D BlancoR S Gibbs
Dec 1, 1985·Archives of Disease in Childhood·A A Attenburrow, C M Barker
Oct 7, 1967·British Medical Journal·W RobertsP Giroud
May 7, 1983·British Medical Journal·G L RidgwayJ D Iriel
May 21, 1983·British Medical Journal·A Mills
Jul 1, 1984·Acta paediatrica Scandinavica·P A MårdhN Svenningsen
Apr 1, 1980·The British Journal of Venereal Diseases·P A MårdhT Nilsson
May 22, 1982·British Medical Journal·D Hobson, E Rees
Sep 1, 1982·American Journal of Diseases of Children·P PatamasuconJ D Nelson
Mar 19, 1982·JAMA : the Journal of the American Medical Association·D H MartinK K Holmes
Jan 1, 1982·Pediatric Infectious Disease·H R HarrisonV A Fulginiti
Jul 1, 1981·British Journal of Obstetrics and Gynaecology·J M RossC R Coid
Nov 21, 1980·JAMA : the Journal of the American Medical Association·M R HammerschlagJ R Smith

Citations

Dec 1, 1994·Advances in Contraception : the Official Journal of the Society for the Advancement of Contraception·J BontisA Sidiropoulou
Feb 27, 2009·Archives of Gynecology and Obstetrics·Işil MaralM Ali Bumin
Dec 16, 1998·Sexually Transmitted Infections·T NyáriI Berbik
Oct 27, 1997·Sexually Transmitted Diseases·J DeákI Berbik
Dec 31, 2009·Obstetrical & Gynecological Survey·Laura E Baecher-LindAllen J Wilcox
Jan 22, 2009·Obstetrics and Gynecology·Catalin S Buhimschi, Carl P Weiner
Oct 22, 2002·Expert Opinion on Pharmacotherapy·Maarten J PostmaServaas A Morré
Jul 27, 2020·The European Respiratory Journal·Evelien R van MeelLiesbeth Duijts

Related Concepts

Chlamydia Infections
Chlamydia trachomatis
Psittacosis
Pregnancy Complications, Infectious

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