Infection of bone by Mycobacterium fortuitum masquerading as Nocardia asteroides

American Journal of Clinical Pathology
J L StaneckE H Miller

Abstract

A case of traumatic osteomyelitis of the leg yielded on culture a branching partially acid-fast organism that failed to respond to therapy directed at Nocardia asteroides. Subsequent laboratory investigation revealed the organism to be Mycobacterium fortuitum. N. asteroides and M. fortuitum can demonstrate similar staining and morphologic patterns microscopically, as well as common colonial and cultural characteristics. Separation can be aided by careful examination of the branching pattern, and can be established by thin-layer chromatography of lipid extracts of the organism. Correct identification of these species in the laboratory is important because of some overlap in their clinical syndromes and because of differences in their susceptibilities to antibiotics.

Citations

Aug 27, 1999·Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society·J G BradyD M Parham
Oct 5, 2002·Clinical Microbiology Reviews·Barbara A Brown-Elliott, Richard J Wallace
May 20, 2000·The Pediatric Infectious Disease Journal·D MironJ M Brown
Jul 1, 1994·Clinical Microbiology Reviews·M M McNeil, J M Brown
Jan 1, 1984·Comparative Immunology, Microbiology and Infectious Diseases·D K Miller-Hardy, B Reynolds

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