Infection of cultured human endothelial cells by Legionella pneumophila.

PloS One
Lucius ChiaraviglioJames E Kirby

Abstract

Legionella pneumophila is a gram-negative pathogen that causes a severe pneumonia known as Legionnaires' disease. Here, we demonstrate for the first time that L. pneumophila infects and grows within cultured human endothelial cells. Endothelial infection may contribute to lung damage observed during Legionnaires' disease and to systemic spread of this organism.

References

Oct 15, 1992·Proceedings of the National Academy of Sciences of the United States of America·A MarraH A Shuman
Mar 3, 1988·The New England Journal of Medicine·L S TompkinsM L Cohen
Nov 1, 1985·Infection and Immunity·A L NewsomeR R Arnold
Apr 1, 1984·Annals of Internal Medicine·R E McCabeK L Vosti
Dec 1, 1981·American Journal of Clinical Pathology·C P Evans, W C Winn
Sep 1, 1980·The Journal of Clinical Investigation·M A Horwitz, S C Silverstein
Apr 1, 1995·Current Microbiology·N P CianciottoD W Kamp
May 1, 1994·Infection and Immunity·L K Husmann, W Johnson
Sep 1, 1993·The Journal of Infection·M FabbiM C Pastoris
Jan 1, 1993·Biometals : an International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine·M T Poch, W Johnson
May 1, 1993·The Journal of Infectious Diseases·C H ModyG B Toews
May 1, 1993·The Journal of Infectious Diseases·B S FieldsE B Shotts
Jul 1, 1996·Infection and Immunity·M S Swanson, R R Isberg
Oct 25, 1996·Annals of the New York Academy of Sciences·M S Swanson, R R Isberg
Sep 4, 1997·The New England Journal of Medicine·J E Stout, V L Yu
Mar 21, 1998·Proceedings of the National Academy of Sciences of the United States of America·G SegalH A Shuman
Mar 4, 1998·Molecular Microbiology·J E KirbyR R Isberg
Apr 29, 1998·The European Respiratory Journal·A MarruchellaP L Chiodera
Jun 25, 1998·American Journal of Respiratory and Critical Care Medicine·K MarutaS Yoshida
Jul 31, 2002·The Journal of Cell Biology·Craig R Roy, Lewis G Tilney
Sep 10, 2003·Proceedings of the National Academy of Sciences of the United States of America·Jen-Tsan ChiPatrick O Brown
Jul 12, 2012·Respiratory Care·Luis Miguel Blasco

❮ Previous
Next ❯

Citations

Oct 15, 2011·Travel Medicine and Infectious Disease·Cyril Guyard, Donald E Low
Feb 13, 2010·Cellular Microbiology·Vicki P LosickRalph R Isberg
Sep 24, 2015·Antimicrobial Agents and Chemotherapy·Lucius Chiaraviglio, James E Kirby
Aug 22, 2020·Journal of Chemotherapy·Md Moinuddin SheamSudhangshu Kumar Biswas
Feb 23, 2010·Molecular and Cellular Biochemistry·Jihee YoonJiho Min

❮ Previous
Next ❯

Methods Mentioned

BETA
transmission electron microscopy

Software Mentioned

IPLab
SAS

Related Concepts

Related Feeds

Aminoglycosides (ASM)

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.

Bacterial Pneumonia (ASM)

Bacterial pneumonia is a prevalent and costly infection that is a significant cause of morbidity and mortality in patients of all ages. Here is the latest research.

Bacterial Pneumonia

Bacterial pneumonia is a prevalent and costly infection that is a significant cause of morbidity and mortality in patients of all ages. Here is the latest research.

Aminoglycosides

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.

© 2022 Meta ULC. All rights reserved