Abstract
Dengue is one of the most important diseases caused by arboviruses in the world. Yellow fever is another arthropod-borne disease of great importance to public health that is endemic to tropical regions of Africa and the Americas. Both yellow fever and dengue viruses are flaviviruses transmitted by Aedes aegypti mosquitoes, and then, it is reasonable to consider that in a given moment, mosquito cells could be coinfected by both viruses. Therefore, we decided to evaluate if sequential infections of dengue and yellow fever viruses (and vice-versa) in mosquito cells could affect the virus replication patterns. Using immunofluorescence and real-time PCR-based replication assays in Aedes albopictus C6/36 cells with single or sequential infections with both viruses, we demonstrated the occurrence of viral interference, also called superinfection exclusion, between these two viruses. Our results show that this interference pattern is particularly evident when cells were first infected with dengue virus and subsequently with yellow fever virus (YFV). Reduction in dengue virus replication, although to a lower extent, was also observed when C6/36 cells were initially infected with YFV followed by dengue virus infection. Although the impor...Continue Reading
References
Nov 1, 1979·The American Journal of Tropical Medicine and Hygiene·R B Tesh
Apr 1, 1979·Journal of Virology·B T Eaton
Nov 1, 1974·Journal of Virology·R E JohnstonH R Bose
Sep 1, 1997·Journal of Virology·A R KarpfD T Brown
Jun 1, 1997·Respirology : Official Journal of the Asian Pacific Society of Respirology·N K ChinW C Tan
Dec 13, 2000·Microbes and Infection·L T Figueiredo
Jan 6, 2001·Memórias do Instituto Oswaldo Cruz·A Prata
May 30, 2001·Journal of Virological Methods·H S HoungN Kanesa-thasan
Jul 21, 2001·Lancet·P F VasconcelosUNKNOWN Brazilian Yellow Fever Vaccine Evaluation Group
Mar 2, 2002·The Lancet Infectious Diseases·T P Monath
Jun 6, 2002·Memórias do Instituto Oswaldo Cruz·Ricardo Lourenço-de-OliveiraAnna-Bella Failloux
Sep 18, 2002·Archives of Medical Research·Duane J Gubler
May 3, 2003·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·María G Guzman, Gustavo Kouri
Jun 14, 2003·Revista Da Sociedade Brasileira De Medicina Tropical·Pedro Fernando da Costa Vasconcelos
Oct 16, 2004·Transactions of the Royal Society of Tropical Medicine and Hygiene·C T CodeçoC J Struchiner
Jun 15, 2007·Revista Da Sociedade Brasileira De Medicina Tropical·Luiz Tadeu Moraes Figueiredo
Nov 13, 2007·Lancet·Scott B Halstead
Apr 1, 2009·Emerging Infectious Diseases·Eric M LeroyXavier De-Lamballerie
May 20, 2009·Microbes and Infection·C PaupyD Fontenille
Mar 20, 2010·Journal of Global Infectious Diseases·Ricardo O IzurietaSten H Vermund
Aug 16, 2011·Bio Systems·Marcos AmakuEduardo Massad
Apr 9, 2013·Nature·Samir BhattSimon I Hay
Apr 14, 2015·Viruses·Bradley J Blitvich, Andrew E Firth
Citations
Sep 18, 2012·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Christine V F Carrington, Albert J Auguste
Nov 11, 2016·PloS One·Nádia Cristina Pinheiro RodriguesIuri da Costa Leite
May 20, 2017·Nature Communications·Claudia RückertGregory D Ebel
Jul 25, 2018·Viruses·Shaun T CrossMark D Stenglein
Aug 4, 2018·Reviews in Medical Virology·Vivian I Avelino-Silva, Esper G Kallas
Jan 23, 2019·Journal of Medical Entomology·Asher M KantorAlexander W E Franz
Aug 2, 2019·Japanese Journal of Infectious Diseases·Hirofumi Ishikawa, Rieko Shimogawara
Jan 15, 2020·Bulletin of Mathematical Biology·Omomayowa Olawoyin, Christopher Kribs
Oct 26, 2018·PLoS Neglected Tropical Diseases·Agathe M G ColmantAndrew F van den Hurk
Jun 13, 2018·Genes·Raphaëlle KlittingXavier de Lamballerie
Dec 6, 2018·Insects·Tereza MagalhaesClaudia Rückert
Dec 2, 2020·Viruses·Goro Kuno
Nov 11, 2020·Viruses·Mathilde LauretiJulio Rodriguez-Andres
Jan 29, 2021·Journal of Travel Medicine·Bethan Cracknell DanielsIlaria Dorigatti