Abstract
Turkey coronavirus (TCoV) is an important viral pathogen causing diarrhoea of young turkey poults that is associated with sizeable economic losses for the turkey industry. Using a field isolate that was found to be free from turkey astrovirus and avian reovirus we were able to reproduce the clinical disease associated with TCoV. Clinical signs and weight gain of poults during experimental infections were compared with age-matched, uninfected controls. Poults infected at 2 days of age had 100% morbidity and 10% mortality, and birds infected at 28 days of age showed 75% morbidity and no mortality. Diarrhoea was consistently seen in infected poults at 2 to 3 days post infection (d.p.i.) with a duration of about 3 to 5 days. Mean body weights of birds infected at 2 or 28 days of age were significantly reduced compared with uninfected birds by 7 d.p.i. and remained significantly lower for the duration of the study. At 44 days of age, poults infected at 2 or 28 days of age weighed only 68.1% or 77.7%, respectively, compared with uninfected turkeys of the same age on the same diet, a mean difference in body weights of 683 or 477g, respectively. Infected birds had profound villus atrophy with some compensatory crypt hyperplasia at 5 to...Continue Reading
References
Aug 26, 1998·Poultry Science·J S Guy
Apr 5, 2000·The Veterinary Record·T W Pennycott
Aug 10, 2000·Revue Scientifique Et Technique·H J BarnesJ P Vaillancourt
Dec 4, 2001·Veterinary Microbiology·Tsang L LinDonna Schrader
Oct 18, 2003·Avian Diseases·M M IsmailY M Saif
Nov 9, 2004·Avian Diseases·Holly S SellersStacey Schultz-Cherry
Dec 29, 2004·Journal of Virological Methods·Silke BruhnHans-Peter Ottiger
May 26, 2005·The Journal of General Virology·Christine Monceyron JonassenAtle Lillehaug
Mar 16, 2006·Avian Pathology : Journal of the W.V.P.A·Dave Cavanagh
Aug 15, 2006·The Veterinary Record·F CulverM P Stevens
Aug 25, 2006·Journal of Virology·Stanley G SawickiStuart G Siddell
Mar 17, 2007·Avian Pathology : Journal of the W.V.P.A·Maria Cecília B TeixeiraTereza C Cardoso
Apr 27, 2007·Journal of Virology·B Q DongY Guan
May 15, 2007·Avian Pathology : Journal of the W.V.P.A·Elena CircellaCanio Buonavoglia
Mar 21, 2008·Journal of Virology·Kathie A MihindukulasuriyaDavid Wang
May 13, 2008·Virus Research·M H GomaaD Yoo
Jul 24, 2008·Avian Diseases·Mary J Pantin-JackwoodErica Spackman
Oct 31, 2008·Journal of Virology·Patrick C Y WooKwok-Yung Yuen
Oct 31, 2008·Clinical and Vaccine Immunology : CVI·Maged H GomaaJohn R Barta
Dec 18, 2008·Avian Pathology : Journal of the W.V.P.A·C NeubauerM Hess
Apr 1, 2001·Avian Pathology : Journal of the W.V.P.A·D Cavanagh
Citations
Apr 19, 2011·Avian Pathology : Journal of the W.V.P.A·S MaurelN Eterradossi
Nov 29, 2013·Avian Diseases·J Michael Day, Laszlo Zsak
Nov 29, 2013·Avian Diseases·Olusegun O AweChang-Won Lee
Feb 13, 2015·Virusdisease·Naresh JindalSagar M Goyal
May 6, 2009·Veterinary Microbiology·Maged H GomaaJohn R Barta
Aug 9, 2015·Archives of Virology·Yi-Ning ChenTsang Long Lin
Jun 13, 2015·Journal of Virology·I N Ambepitiya WickramasingheM H Verheije
Dec 17, 2020·Animals : an Open Access Journal From MDPI·Valentina ZappulliMassimo Castagnaro
Jul 2, 2021·Veterinary Microbiology·Kyung-Il KangQingzhong Yu