PMID: 6985886Jan 1, 1980Paper

Infections and antibiotic prophylaxis in the fulgurated rat bladder

Investigative Urology
D H BagleyE J McGuire

Abstract

A model is described for establishing infection in a fulgurated rat bladder. Persistence of bacteriuria was dependent upon the size of the bacterial inoculum. Infection in an injured bladder exposed to a single predictable bacterial inoculum may be prevented by a single dose of antibiotic. The appropriate timing of antibiotic administration varies with the infecting organism.

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