Infectious complications in autosomal dominant polycystic kidney disease

Néphrologie & thérapeutique
Y Pirson, Nada Kanaan

Abstract

Despite advances in the management of autosomal dominant polycystic kidney disease over the past two decades, infection of liver and kidney cysts remains a serious and potentially threatening complication. Kidney cyst infection is the most frequent complication. It is differentiated from hemorrhage by the clinical presentation (mainly the severity and duration of fever), C-reactive protein (CRP) and white blood cells levels, and the density of the suspected cyst on computed tomography. Liver cyst infection occurs more frequently in patients with large cysts volumes. It can be life threatening and has a tendency to recur. In both infections, the best radiological imaging technique is positron emission tomography after intravenous injection of [18F]-fluorodeoxyglucose combined with computed tomography. Treatment with a fluoroquinolone should be continued for 6 weeks. Cyst aspiration is necessary only when cysts are very large and/or when infection is resistant to antibiotic treatment. In patients who are candidates to kidney transplantation, a history of recurrent kidney cyst infection justifies pre-transplant nephrectomy, while a past history of recurrent liver cyst infection or angiocholitis leads to consider liver transplantat...Continue Reading

References

Jul 1, 1996·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·J L ChristopheY Pirson
Sep 29, 2001·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·R D PerroneN C Terrin
Nov 2, 2004·Transplant International : Official Journal of the European Society for Organ Transplantation·Susanna SarkioKaija Salmela
Dec 22, 2004·Kidney International·Hisato Takagi, Takuya Umemoto
Apr 17, 2007·Lancet·Vicente E TorresYves Pirson
May 28, 2009·Clinical Journal of the American Society of Nephrology : CJASN·Marion SalléeFadi Fakhouri
Jun 12, 2009·Liver International : Official Journal of the International Association for the Study of the Liver·Esmé WaandersJoost P H Drenth
Dec 25, 2009·Radiology·Bachir Taouli, Dow-Mu Koh
Mar 2, 2010·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Nada KanaanZiad Hassoun
Mar 12, 2010·Advances in Chronic Kidney Disease·Yves Pirson
Jun 28, 2011·Clinical Journal of the American Society of Nephrology : CJASN·François JouretNada Kanaan
Jun 13, 2012·Clinical and Experimental Nephrology·Tatsuya SuwabeKenmei Takaichi
Nov 2, 2012·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·François JouretNada Kanaan
Nov 12, 2013·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Randy L Luciano, Neera K Dahl
Jun 18, 2014·Nature Reviews. Nephrology·Nada KanaanYves Pirson

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Citations

Aug 25, 2015·Case Reports in Nephrology·Nikos SabanisSotirios Vasileiou
Oct 6, 2015·Transplant Infectious Disease : an Official Journal of the Transplantation Society·A TamigniauV Saegeman
Jul 30, 2015·La Radiologia medica·Arthur RobertFred E Avni
May 9, 2019·Canadian Journal of Kidney Health and Disease·Caroline LamarcheThomas Kitzler

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