Infectious complications of pancreatitis: diagnosis and management

Current Gastroenterology Reports
Girish Mishra, Benoit C Pineau

Abstract

Infected pancreatic necrosis is the leading cause of death in patients with severe acute pancreatitis. Early prophylactic antibiotic treatment is effective in preventing conversion of sterile necrosis to pancreatic infection, but its effect on mortality remains unproven. Fungal infections may predict a worse outcome, but no evidence supports the use of antifungal prophylaxis. Because infection of pancreatic necrosis by enteric bacteria can develop despite prophylaxis, a high index of suspicion should allow early detection followed by aggressive management.

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Citations

Apr 1, 2006·American Journal of Respiratory Cell and Molecular Biology·Naoyuki MatsudaYuichi Hattori
Nov 15, 2006·World Journal of Surgery·José M Remes-TrocheGuillermo Robles-Díaz
Jul 19, 2013·Digestive Diseases and Sciences·Yueqiu QinSien Song
Sep 15, 2015·Journal of the Belgian Society of Radiology·A Van HolsbeeckK Ramboer
Aug 3, 2021·Gastroenterology Research and Practice·Xiaowu Dong Chinese Acute Pancreatitis Clinical Trials Group Capctg

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