journal cover

Infectious stimuli promote malignant B-cell acute lymphoblastic leukemia in the absence of AID

Nature Communications

Dec 6, 2019

Guillermo Rodríguez-HernándezArndt Borkhardt

Abstract

The prerequisite to prevent childhood B-cell acute lymphoblastic leukemia (B-ALL) is to decipher its etiology. The current model suggests that infection triggers B-ALL development through induction of activation-induced cytidine deaminase (AID; also known as AICDA) in precursor B-cells....read more

Mentioned in this Paper

Cytidine Deaminase Activity
Study
Cytidine Deaminase
Chemically Induced
B-Lymphocytes
Precursor B-cell Lymphoblastic Leukemia
Transplantation
ANKS1B protein, human
Cell Transformation
Activation-Induced Cytidine Deaminase
8
Paper Details
References
  • References66
  • Citations
12345...
  • References66
  • Citations
  • quote and clock

    No citations available

    This paper may not have been cited yet.

Infectious stimuli promote malignant B-cell acute lymphoblastic leukemia in the absence of AID

Nature Communications

Dec 6, 2019

Guillermo Rodríguez-HernándezArndt Borkhardt

PMID: 31804490

DOI: 10.1038/s41467-019-13570-y

Abstract

The prerequisite to prevent childhood B-cell acute lymphoblastic leukemia (B-ALL) is to decipher its etiology. The current model suggests that infection triggers B-ALL development through induction of activation-induced cytidine deaminase (AID; also known as AICDA) in precursor B-cells....read more

Mentioned in this Paper

Cytidine Deaminase Activity
Study
Cytidine Deaminase
Chemically Induced
B-Lymphocytes
Precursor B-cell Lymphoblastic Leukemia
Transplantation
ANKS1B protein, human
Cell Transformation
Activation-Induced Cytidine Deaminase
8

Related Papers

Paper Details
References
  • References66
  • Citations
12345...
  • References66
  • Citations
  • quote and clock

    No citations available

    This paper may not have been cited yet.
/papers/infectious-stimuli-promote-malignant-b-cell-acute/31804490