Infective endocarditis in children--incidence, pattern, diagnosis and management in a developing country

International Journal of Cardiology
M SadiqS A Sheikh

Abstract

In developing countries, patients with infective endocarditis are referred late, there is low yield of blood cultures and incidence of rheumatic heart disease is still high. Evaluate clinical pattern, assess diagnostic criteria in our settings and determine outcome. A tertiary referral center for paediatric and adult cardiology. All children with infective endocarditis admitted to a single center from April 1997 to March 2000 were analysed. The diagnosis was based on Duke's criteria, which proposed two major and six minor criteria. Minor criteria were expanded to include raised acute phase reactants and presence of newly diagnosed or increasing splenomegally. The patients were stratified as definite, possible and rejected cases. Of 1402 hospital admissions, 45 patients fulfilled the diagnostic criteria for infective endocarditis giving an incidence of 32 per 1000 hospital admissions. The mean age was 7.9 +/- 4 years (4 months to 16 years) with only two patients under 1 year of age. Rheumatic heart disease was the underlying lesion in 24 patients (53%) while congenital heart lesions occurred in 20 patients (45%). Previous antibiotic treatment was given in 26 patients (58%) definitely. Blood cultures were positive in 21 patients ...Continue Reading

References

Dec 1, 1992·The American Journal of Cardiology·R ChoudhuryR P Sapru
Oct 1, 1992·Pediatric Cardiology·D HansenJ R Jacobsen
Apr 15, 1991·Annals of Internal Medicine·J M SteckelbergW R Wilson
Jul 1, 1991·The American Journal of Cardiology·S M AwadallahM S Blackman
Mar 1, 1990·International Journal of Cardiology·D A MarshallS M Cobbe
Jun 28, 1985·The American Journal of Medicine·S G AlsipC G Cobbs
Apr 1, 1986·Annals of Internal Medicine·H C Sox, M H Liang
Sep 1, 1983·American Journal of Diseases of Children·R E KaveyE L Bove
Feb 1, 1984·Archives of Internal Medicine·T H LeG Chomette
Apr 1, 1981·Annals of Internal Medicine·C F Von ReynC S Crumpacker
Apr 1, 1995·European Heart Journal·J NormandH Le Bris
Mar 1, 1995·The Annals of Thoracic Surgery·M SadiqB Sethia

❮ Previous
Next ❯

Citations

Apr 26, 2003·International Journal of Cardiology·Andrew J S Coats
Oct 2, 2013·Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine·Ashish GuptaAmit Varma
Dec 30, 2014·Advanced Biomedical Research·Alireza Ahmadi, Hooman Daryushi
Jul 21, 2011·European Journal of Pediatrics·Walter Knirsch, David Nadal
Jan 29, 2016·Cardiology in the Young·I Levent SaltıkAyşe G Eroglu
Jun 14, 2013·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·E CarpentierP Tourneux
Jul 2, 2011·The Annals of Thoracic Surgery·Mauro Lo RitoAldo R Castañeda
Jan 10, 2009·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Bilal Karim SiddiquiRaymond A Smego
Apr 28, 2004·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Muhammad TariqRaymond A Smego
Sep 26, 2013·Circulation·Barbara J M Mulder
Jan 1, 2014·The Pediatric Infectious Disease Journal·Rachel WebbDiana Lennon
Aug 6, 2021·International Journal of Pediatrics & Adolescent Medicine·Tala AlBassriMohamed S Kabbani

❮ Previous
Next ❯

Related Concepts

Related Feeds

Birth Defects

Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.

© 2021 Meta ULC. All rights reserved