To provide pure cohorts of paediatric and adult patients with congenital heart disease (CHD) and infective endocarditis (IE) for making future guidelines. Japanese nationwide survey. 66 Japanese institutions. 170 children, mean (SD) age 7.4 (5.7) years (range 14 days to 17 years), and 69 adults, age 32.5 (14.1) years (range 18-69) who developed IE between 1997 and 2001 (one in 240 admissions with CHD). Clinical presentation of IE. 119 patients including 88 with cyanotic CHD had previous cardiac surgery. Procedures preceding IE were dental (12%) followed by cardiovascular surgery (8%). Sites of infection were left sided in 46% and right sided in 51%. Vegetation with diameter of 11 mm was documented in 151 (63%). Frequent complications were embolic events (stroke 11%, other emboli 20%) and cardiac failure (23%). The most common microorganisms were streptococci (50%) and staphylococci (37%) with methicillin resistant Staphylococcus aureus in 7.5%. Empirical treatments were penicillins (alone or with other antibiotics 57%) followed by cephems (22%) and vancomycin (11%). Surgery during active IE was common (26%), with vegetation (45%) and heart failure (29%) as the most frequent indications. Mortality was 8.8%: 8.0% among patients w...Continue Reading
A collaborative study of infective endocarditis in the 1970s. Emphasis on infections in patients who have undergone cardiovascular surgery
Echocardiographic assessment of patients with infectious endocarditis: prediction of risk for complications
Staphylococcus aureus bacteremia. Clinical, serologic, and echocardiographic findings in patients with and without endocarditis
Infective endocarditis in children with congenital heart disease: comparison of selected features in patients with surgical correction or palliation and those without
Apparent failures of endocarditis prophylaxis. Analysis of 52 cases submitted to a national registry
Survey of prophylaxis and management of infective endocarditis in patients with congenital heart disease: Japanese nationwide survey
Current characteristics of infective endocarditis in Japan: an analysis of 848 cases in 2000 and 2001
Guidelines on prevention, diagnosis and treatment of infective endocarditis executive summary; the task force on infective endocarditis of the European society of cardiology
Successful surgical treatment for methicillin-resistant Staphylococcus aureus endocarditis on the ventricular rerouting patch after a Rastelli operation
Guidelines on the prevention, diagnosis, and treatment of infective endocarditis (new version 2009): the Task Force on the Prevention, Diagnosis, and Treatment of Infective Endocarditis of the European Society of Cardiology (ESC). Endorsed by the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) and the International Society of Chemotherapy (ISC) for Infection and Cancer
Turning 18 with congenital heart disease: prediction of infective endocarditis based on a large population
Infective endocarditis in adults with congenital heart disease: is it time to change our approach to prophylaxis based on new insights into risk prediction?
A 72-year-old woman with an uncorrected tetralogy of Fallot presenting with possible pulmonary endocarditis: a case report
Changing profile of infective endocarditis: a clinicopathologic study of 220 patients in a single medical center from 1998 through 2009
Infective endocarditis in adult patients with congenital heart disease. Experience from a reference centre
Infective endocarditis prophylaxis: current practice trend among paediatric cardiologists: are we following the 2007 guidelines?
A 15-year-old boy with congenital heart disease, fevers, and acute onset of dysarthria: infective endocarditis
Molecular analyses of bacterial DNA in extirpated heart valves from patients with infective endocarditis
Detection and serotype distribution of Actinobacillus actinomycetemcomitans in cardiovascular specimens from Japanese patients
Infective endocarditis complicated by fatal cerebral hemorrhage revealing an unrepaired univentricular heart in a 19-year-old woman
Two- and live/real time three-dimensional transthoracic echocardiographic assessment of infective endocarditis of a valved pulmonary conduit
Incidence and outcomes of right-sided endocarditis in patients with congenital heart disease after surgical or transcatheter pulmonary valve implantation
Risk factors for in-hospital mortality during infective endocarditis in patients with congenital heart disease
Amoxicillin-resistant oral streptococci identified in dental plaque specimens from healthy Japanese adults
ACC/AHA 2008 guidelines for the management of adults with congenital heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Develop Guidelines on the Management of Adults With Congenital Heart Disease). Developed in Collaboration With the American Society of Echocardiography, Heart Rhythm Society, International Society for Adult Congenital Heart Disease, Society for Cardiovascular Angiography and Interventions, and Soc
Stroke in children with cardiac disease: report from the International Pediatric Stroke Study Group Symposium
Changes in patient characteristics of infective endocarditis with congenital heart disease: 25 years experience in a single institution
Antibiotic duration and timing of the switch from intravenous to oral route for bacterial infections in children: systematic review and guidelines
Infective endocarditis after device closure of atrial septal defects: Case report and review of the literature
Inaccuracy of transthoracic echocardiography for the identification of right-sided vegetation in patients with no history of intravenous drug abuse or cardiac device insertion
Endocarditis in children and adolescents with congenital heart defects: a Norwegian nationwide register-based cohort study
ACC/AHA 2008 Guidelines for the Management of Adults with Congenital Heart Disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (writing committee to develop guidelines on the management of adults with congenital heart disease)
Infective Endocarditis in Childhood: 2015 Update: A Scientific Statement From the American Heart Association
A septic pulmonary embolism associated with right-sided infective endocarditis and a ventricular septal defect in a patient with atopic dermatitis
Predictive factors of death associated with infective endocarditis in adult patients with congenital heart disease
Multimodality Imaging in the Diagnostic Work-Up of Endocarditis and Cardiac Implantable Electronic Device (CIED) Infection
Management of Stroke in Neonates and Children: A Scientific Statement From the American Heart Association/American Stroke Association
Coxiella Endocarditis as the Cause of Recurrent Fever and Brain Abscess in a Patient with Complex Congenital Heart Disease: A Case Report and Literature Review
Wait, not so fast. Are the new American Heart Association endocarditis prophylaxis guidelines safe, and where is the proof?
The pivotal role of cardiac computed tomography angiogram and 18 F-fluorodeoxyglucose positron emission tomography-computed tomography in the diagnosis of right sided endocarditis: a case report
2015 ESC Guidelines for the management of infective endocarditis: The Task Force for the Management of Infective Endocarditis of the European Society of Cardiology (ESC). Endorsed by: European Association for Cardio-Thoracic Surgery (EACTS), the European Association of Nuclear Medicine (EANM)
Predictive factors of death associated with infective endocarditis in adult patients with congenital heart disease.
Usefulness of 18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in the Diagnosis of Infective Endocarditis in Patients With Adult Congenital Heart Disease.
Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.