PMID: 11322373Apr 27, 2001Paper

Inferior vena cava indices determine volume load in minimal lesion nephrotic syndrome

Pediatric Nephrology : Journal of the International Pediatric Nephrology Association
O DönmezC Kabasakal

Abstract

The pathogenesis of edema in nephrotic syndrome has not been entirely understood. We investigated the value of the echographic parameters [inferior vena cava index (IVCI), inferior vena cava collapsibility index (IVCCI), and left atrium diameter (LAD)] to determine the volume load in children with minimal lesion nephrotic syndrome (MLNS). Twelve children with MLNS (seven boys, five girls) were included in this study. The patients were classified into three different stages (stage A: edematous; stage B: 50% decrease in weight gain; stage C: edema free) following measurement of their ideal weights. The ideal weight of patients in stage A was increased 13 +/- 7%. Serum total protein, albumin and urine sodium levels were found to be low in these patients. Plasma renin activity (PRA) and serum aldosterone levels in stage A were significantly different from those of the control group (P<0.05). PRA and serum aldosterone levels were not different from those of the control group in stage B (P>0.05). However, the increase in PRA was significant in stage C. Although a significant weight decrease was found in stages B and C, it had no effect on IVCI, LAD, and cardiothoracic index. We consider IVCI, IVCCI, and LAD measurements by echocardio...Continue Reading

Citations

Apr 17, 2008·International Urology and Nephrology·Yilmaz TabelSerdal Gungor
Jan 17, 2013·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·René F AndersenSøren Rittig
Mar 5, 2011·Circulation Journal : Official Journal of the Japanese Circulation Society·Yoichi IwamotoHideaki Senzaki
Dec 27, 2011·The Journal of Emergency Medicine·Robert A De LorenzoJuanita S Medina
Jun 25, 2010·Pediatrics International : Official Journal of the Japan Pediatric Society·Metin Kaya GurgozeRuhan Dusunsel
Feb 6, 2015·Clinical and Experimental Nephrology·Yoshitsugu KakuUNKNOWN Japanese Society for Pediatric Nephrology
Jul 15, 2017·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Anna Jarosz-LeszIwona Maruniak-Chudek
Apr 2, 2020·Indian Journal of Pediatrics·Jitendra Meena, Arvind Bagga

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