Apr 9, 2020

Endemic island songbirds as windows into evolution in small effective population sizes

BioRxiv : the Preprint Server for Biology
Thibault LeroyB. Nabholz


Due to their limited ranges and inherent isolation, island species provide a unique opportunity to study the impact of non-adaptive forces on molecular evolution, especially how effective population size may influence the accumulation of deleterious mutations. By estimating nucleotide diversity at synonymous and non-synonymous sites for a large set of in-house and published whole genome sequences covering distant phylogenetic taxa (14 endemic insular and 11 mainland passerine bird species), we found support for contrasted patterns of molecular variation between endemic island and mainland species. Even after controlling for the phylogenetic inertia, we observed significantly lower nucleotide diversities, higher mutation loads and lower adaptive substitution rates in the endemic insular species. Overall, our results indicate that the smaller area available on islands likely constrains the upper bound of the effective population size, in such a way that demography has affected the ability of natural selection to efficiently remove weakly deleterious mutations. Endemic insular species genomes therefore represent excellent windows into evolution in small effective population sizes and we discussed the implications for both evolutio...Continue Reading

  • References
  • Citations


  • We're still populating references for this paper, please check back later.
  • References
  • Citations


  • This paper may not have been cited yet.

Mentioned in this Paper

Signaling Molecule
Gene Expression
RNA, Messenger
Escherichia coli
Posterior Pituitary Disease
Computed (Procedure)

Related Feeds

BioRxiv & MedRxiv Preprints

BioRxiv and MedRxiv are the preprint servers for biology and health sciences respectively, operated by Cold Spring Harbor Laboratory. Here are the latest preprint articles (which are not peer-reviewed) from BioRxiv and MedRxiv.

Related Papers

Genome Biology and Evolution
Jennifer E JamesAdam Eyre-Walker
Proceedings. Biological Sciences
Megan Woolfit, Lindell Bromham
Evolution; International Journal of Organic Evolution
Robert P Anderson, Charles O Handley
Evolution; International Journal of Organic Evolution
Pasquale Raia, Shai Meiri
© 2020 Meta ULC. All rights reserved