journal cover

Inferring Population Structure and Admixture Proportions in Low-Depth NGS Data

Genetics

Aug 23, 2018

Jonas Meisner, Anders Albrechtsen

Abstract

We here present two methods for inferring population structure and admixture proportions in low-depth next-generation sequencing (NGS) data. Inference of population structure is essential in both population genetics and association studies, and is often performed using principal compone...read more

Mentioned in this Paper

Computer Software
Non-negative Matrix Factorization
Study
Heuristics
Extracellular Matrix
Complement Component 2 Deficiency
Genetics, Population
Statistical Cluster
TAPBP protein, human
Sequencing
2
80
Paper Details
References
  • References
  • Citations11
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
  • References
  • Citations11
12

Trending Feeds

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

GTPases in Intracellular Trafficking

GTPases, including small ras sub-families and large dynamin are regulators of intracellular trafficking. They are implicated in vesicular transport and important for the communication within cells. Discover the latest search on GTPases in intracellular trafficking here.

Coronavirus

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the Middle East Respiratory Syndrome, Severe Acute Respiratory Syndrome, and 2019-nCov. Coronaviruses can spread from animals to humans. Symptoms include fever, cough, shortness of breath, and breathing difficulties. In more severe cases, it can lead to death. Here is the latest research on coronaviruses.

Cell Atlas of the Human Eye

Constructing a cell atlas of the human eye will require transcriptomic and histologic analysis over the lifespan. This understanding will aid in the study of development and disease. Find the latest research pertaining to the Cell Atlas of the Human Eye here.

Membranoproliferative Glomerulonephritis

Membranoproliferative glomerulonephritis is type of Chronic glomerulonephritis characterized histologically by proliferation of mesangial cells, increase in the mesangial extracellular matrix, and a thickening of the glomerular capillary walls. Discover the latest research on membranoproliferative glomerulonephritis here.

Severe Acute Respiratory Syndrome

Severe acute respiratory syndrome (SARS) is a viral respiratory disease of zoonotic origin caused by the SARS coronavirus (SARS-CoV). Initial symptoms are flu-like and may include fever, muscle pain, lethargy symptoms, cough, sore throat, and other nonspecific symptoms. SARS may eventually lead to shortness of breath and pneumonia; either direct viral pneumonia or secondary bacterial pneumonia. DIscover the latest research on SARS here.

Microbiome and MS

Multiple sclerosis (MS) is the most common chronic inflammatory disease of the central nervous system which is characterized by inflammatory demyelination and neurodegeneration. Here is the latest research on the influence of the human microbiome on this dymyelinating disorder.

Notch-Instructed 3D Cancer Genomes (Keystone)

Cancer genomics employ high-throughput technologies to identify the complete catalog of somatic alterations that characterize the genome, transcriptome and epigenome of cohorts of tumor samples. This feed focuses on Notch-instructed 3D cancer genomes. Discover the latest research here.

Related Papers

Genetics

Estimating individual admixture proportions from next generation sequencing data

GeneticsSeptember 13, 2013
Line SkotteAnders Albrechtsen
Bioinformatics

fastNGSadmix: admixture proportions and principal component analysis of a single NGS sample

BioinformaticsSeptember 29, 2017
Emil JørsboeAnders Albrechtsen
© 2020 Meta ULC. All rights reserved

Inferring Population Structure and Admixture Proportions in Low-Depth NGS Data

Genetics

Aug 23, 2018

Jonas Meisner, Anders Albrechtsen

PMID: 30131346

DOI: 10.1534/genetics.118.301336

Abstract

We here present two methods for inferring population structure and admixture proportions in low-depth next-generation sequencing (NGS) data. Inference of population structure is essential in both population genetics and association studies, and is often performed using principal compone...read more

Mentioned in this Paper

Computer Software
Non-negative Matrix Factorization
Study
Heuristics
Extracellular Matrix
Complement Component 2 Deficiency
Genetics, Population
Statistical Cluster
TAPBP protein, human
Sequencing
2
80

Trending Feeds

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Related Papers

Genetics

Estimating individual admixture proportions from next generation sequencing data

GeneticsSeptember 13, 2013
Line SkotteAnders Albrechtsen
Bioinformatics

fastNGSadmix: admixture proportions and principal component analysis of a single NGS sample

BioinformaticsSeptember 29, 2017
Emil JørsboeAnders Albrechtsen
Paper Details
References
  • References
  • Citations11
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
  • References
  • Citations11
12
/papers/inferring-population-structure-and-admixture/30131346