journal cover

Inferring restrictions in the temporal order of mutations during tumor progression: effects of passenger mutations, evolutionary models, and sampling

bioRxiv

May 27, 2014

Ramon Diaz-Uriarte

Abstract

In cancer progression, fixation of some driver mutations (those causally involved in the disease) can depend on the presence of other drivers. The majority of mutations present in cancer cells, however, are not drivers but passenger mutations that are not involved in disease progression...read more

Mentioned in this Paper

Fluid Sample Cell Count Measurement
Sample Fixation
Evaluation
Mutation Abnormality
Embedding
Disease Progression
Cancer Progression
Equus asinus
Tumor Cells, Malignant
Trees (plant)
2
12
Paper Details
References
  • References
  • Citations
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
  • References
  • Citations
  • quote and clock

    No citations available

    This paper may not have been cited yet.

Inferring restrictions in the temporal order of mutations during tumor progression: effects of passenger mutations, evolutionary models, and sampling

bioRxiv

May 27, 2014

Ramon Diaz-Uriarte

PMID: 990005587

DOI: 10.1101/005587

Abstract

In cancer progression, fixation of some driver mutations (those causally involved in the disease) can depend on the presence of other drivers. The majority of mutations present in cancer cells, however, are not drivers but passenger mutations that are not involved in disease progression...read more

Mentioned in this Paper

Fluid Sample Cell Count Measurement
Sample Fixation
Evaluation
Mutation Abnormality
Embedding
Disease Progression
Cancer Progression
Equus asinus
Tumor Cells, Malignant
Trees (plant)
2
12
Paper Details
References
  • References
  • Citations
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
  • References
  • Citations
  • quote and clock

    No citations available

    This paper may not have been cited yet.
/papers/inferring-restrictions-in-the-temporal-order-of/990005587