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Inferring restrictions in the temporal order of mutations during tumor progression: effects of passengers, evolutionary models, and sampling

bioRxiv

May 27, 2014

Ramon Diaz-Uriarte

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Abstract

Cancer progression is caused by the sequential accumulation of mutations, but not all orders of accumulation of mutations are equally likely. When the fixation of some mutations depends on the presence of previous ones, identifying restrictions in the order of accumulation of mutations ...read more

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Sampling - Surgical Action
Tumor Cells, Malignant
Evaluation
Equus asinus
Mutation Abnormality
Fluid Sample Cell Count Measurement
Sample Fixation
Tumor Progression
Metric
Disease Progression
2
Paper Details
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  • Inferring restrictions in the temporal order of mutations during tumor progression: effects of passengers, evolutionary models, and sampling

    bioRxiv

    May 27, 2014

    Ramon Diaz-Uriarte

    PMID: 990005587

    DOI: 10.1101/005587

    Abstract

    Cancer progression is caused by the sequential accumulation of mutations, but not all orders of accumulation of mutations are equally likely. When the fixation of some mutations depends on the presence of previous ones, identifying restrictions in the order of accumulation of mutations ...read more

    Mentioned in this Paper

    Sampling - Surgical Action
    Tumor Cells, Malignant
    Evaluation
    Equus asinus
    Mutation Abnormality
    2
    Paper Details
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