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Inferring the demographic history and rate of adaptive substitution in Drosophila

PLoS Genetics

Oct 13, 2006

Hai-Peng Li, Wolfgang Stephan

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Abstract

An important goal of population genetics is to determine the forces that have shaped the pattern of genetic variation in natural populations. We developed a maximum likelihood method that allows us to infer demographic changes and detect recent positive selection (selective sweeps) in p...read more

Mentioned in this Paper

Sampling - Surgical Action
Dipodomys simulans
Dioscorea simulans
X Chromosome
Anatomy, Regional
Drosophila melanogaster
Intergenic Region
Single Nucleotide Polymorphism
Mutagenesis Process
Genetic Polymorphism
168
Paper Details
References
    • References35
    • Citations130
    • References35
    • Citations130
  • Inferring the demographic history and rate of adaptive substitution in Drosophila

    PLoS Genetics

    Oct 13, 2006

    Hai-Peng Li, Wolfgang Stephan

    PMID: 17040129

    DOI: 10.1371/journal.pgen.0020166

    Abstract

    An important goal of population genetics is to determine the forces that have shaped the pattern of genetic variation in natural populations. We developed a maximum likelihood method that allows us to infer demographic changes and detect recent positive selection (selective sweeps) in p...read more

    Mentioned in this Paper

    Sampling - Surgical Action
    Dipodomys simulans
    Dioscorea simulans
    X Chromosome
    Anatomy, Regional
    168
    Paper Details
    References
    • References35
    • Citations130
    • References35
    • Citations130
  • Get paper from

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