Inflammasomes in aspergillosis--it takes two to tango

Cell Host & Microbe
Jeffrey Tomalka, Amy G Hise

Abstract

Intracellular inflammasome complexes regulate critical cytokine responses to infections. In this issue of Cell Host & Microbe,Karki et al. (2015) show that protection against the fungus Aspergillus requires the combined efforts of the NLRP3 and AIM2 inflammasomes and involves both caspase-1 and caspase-8.

Citations

Jul 15, 2015·International Reviews of Immunology·Beáta SoltészLászló Maródi

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