PMID: 9532250Aug 1, 1997Paper

Inflammation markers and symptom activity in children with bronchial asthma. Influence of atopy and eczema

Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology
K H CarlsenK C Carlsen

Abstract

Eosinophil cationic protein (ECP) has been reported to reflect the eosinophil inflammatory activity in asthma. However, the relative impact of asthma symptoms and atopic eczema upon serum (s)-ECP in asthmatic children has not been established. To examine s-ECP levels and s-myeloperoxidase (MPO) in relation to asthma symptoms and atopic eczema in asthmatic children. S-ECP and s-MPO were assessed in relation to symptom activity, lung function, exercise-induced bronchoconstriction and bronchial responsiveness in 101 children; median age 9 years, range 1-16 years; with moderate to severe asthma, admitted to Voksentoppen Center. S-ECP was significantly higher in children with persistent compared to episodic or no asthma symptoms in the past four weeks. S-ECP was also higher in children with atopic compared to non-atopic asthma, as well as in those with active compared to past history or no history of atopic eczema. S-MPO was higher in children with persistent asthma symptoms, but did not differ in relation to atopy or eczema state. Persistent asthma symptoms had the greatest impact upon s-ECP levels, followed by atopy and active eczema. S-ECP may be used in assessing symptom activity in asthmatic children, but with the realisation t...Continue Reading

References

Jan 1, 1992·Dermatology : International Journal for Clinical and Investigative Dermatology·M K KägiB Wüthrich
Feb 1, 1992·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·T SugaiS Matumoto
Sep 1, 1991·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·C G PetersonP Venge
Oct 11, 1990·The New England Journal of Medicine·J BousquetP Godard
Nov 1, 1981·The Journal of Allergy and Clinical Immunology·F E HargreaveJ Dolovich
Oct 1, 1995·The Journal of Pediatrics·J M IngramP W Heymann
Jul 1, 1995·The European Respiratory Journal·K C Lødrup CarlsenK H Carlsen
Aug 1, 1995·American Journal of Respiratory and Critical Care Medicine·D Y KollerM Götz
Jan 1, 1995·The Journal of Allergy and Clinical Immunology·A C FergusonC Curtis
Nov 1, 1994·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·S KristjánssonG Wennergren
Nov 1, 1994·American Journal of Respiratory and Critical Care Medicine·L A Laitinen, A Laitinen
Jul 1, 1993·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·B ZimmermanS Ahlstedt
Nov 1, 1995·Archives of Disease in Childhood·D Y KollerI Eichler
Apr 1, 1996·Allergy·S Bonini
Jul 1, 1996·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·R RaoJ O Warner
Mar 1, 1993·The European Respiratory Journal·P J SterkJ L Malo

❮ Previous
Next ❯

Citations

Jan 10, 2004·The Journal of Allergy and Clinical Immunology·Christina MirandaSally E Wenzel
May 17, 2000·Current Opinion in Pulmonary Medicine·A Niimi, H Matsumoto
Aug 10, 2000·American Journal of Respiratory and Critical Care Medicine·N Wilson, S Pedersen
Aug 30, 2002·Allergologia et immunopathologia·Wassim Khalil Kalaajieh, Rémi Hoilat
Aug 13, 2003·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·O D Wolthers
Nov 1, 2006·Allergy·G ByremoK H Carlsen
Feb 11, 2010·Pediatric Pulmonology·Mari K HyvärinenMatti Korppi
Jan 18, 2003·Paediatric Respiratory Reviews·G Wennergren
Mar 22, 2001·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·K M SaarinenE Savilahti
Nov 14, 1998·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·T N Bryant
Oct 16, 1999·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·M D ShieldsM Ennis
Jun 26, 1999·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·M O Hoekstra
Jul 25, 1998·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·J O Warner
Mar 17, 2001·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·K Oymar, R Bjerknes
May 10, 2017·Fetal and Pediatric Pathology·Aleksandra TopicDragica Radojkovic
Mar 1, 2020·Antioxidants·Lucrezia BertinoSebastiano Gangemi
Jan 21, 2021·Journal of Asthma and Allergy·Stefan ZielenKatharina Blumchen

❮ Previous
Next ❯

Related Concepts

Related Feeds

Atopic Dermatitis

Atopic dermatitis is a chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. Discover the latest research on atopic dermatitis here.

Asthma

This feed focuses in Asthma in which your airways narrow and swell. This can make breathing difficult and trigger coughing, wheezing and shortness of breath.

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.