PMID: 8949450Sep 1, 1996Paper

Inflammation of solar keratoses following systemic 5-fluorouracil

The British Journal of Dermatology
V BatailleP Mortimer

Abstract

Several cutaneous reactions have been reported following systemic 5-fluorouracil (5-FU) for the treatment of malignancies. We report three patients with marked inflammation of the solar keratoses following continuous infusion of 5-FU for solid tumours. This side-effect with 5-FU, only previously reported in three other cases, was beneficial as most solar keratoses cleared following the inflammatory reaction. The reasons why 5-FU should be selectively taken up by solar keratoses are discussed.

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Citations

Dec 10, 1997·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·R A Schwartz
Mar 10, 1999·Journal of the American Academy of Dermatology·W S SusserJ M Grant-Kels
Apr 9, 2005·Clinics in Plastic Surgery·Anjali K ButaniRobert A Schwartz

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