Inflammatory and Infectious Processes Serve as Links between Atrial Fibrillation and Alzheimer's Disease

International Journal of Molecular Sciences
Gabriela Lopes MartinsHelton José Reis

Abstract

Atrial fibrillation (AF) is one of the most prevalent forms of arrhythmia that carries an increased risk of stroke which, in turn, is strongly associated with cognitive decline. The majority of dementia cases are caused by Alzheimer's disease (AD) with obscure pathogenesis. While the exact mechanisms are unknown, the role of inflammatory processes and infectious agents have recently been implicated in both AD and AF, suggesting a common link between these maladies. Here, we present the main shared pathways underlying arrhythmia and memory loss. The overlapping predictive biomarkers and emerging joint pharmacological approaches are also discussed.

References

Jun 20, 2000·Neurobiology of Aging·H AkiyamaT Wyss-Coray
Jun 14, 2001·Alzheimer Disease and Associated Disorders·P S AisenM Fusco
Jul 7, 2001·American Journal of Therapeutics·A K AslamI A Khan
Mar 31, 2004·Experimental Cell Research·Rodrigo A QuintanillaRicardo B Maccioni
Nov 17, 2004·Annals of Internal Medicine·Li WeiBrian R Walker
Nov 27, 2004·European Archives of Psychiatry and Clinical Neuroscience·Harald HampelHans-Jürgen Möller
Mar 1, 2005·The Annals of Thoracic Surgery·Kaushik MandalMarjan Jahangiri
Aug 3, 2005·Drugs & Aging·Philippe BordierAlexia Lafitte
Nov 3, 2005·The European Journal of Neuroscience·Fei LiuCheng-Xin Gong
Jan 13, 2006·Cardiovascular Research·Akiko Shiroshita-TakeshitaStanley Nattel
May 10, 2006·Archives of Internal Medicine·Chengxuan QiuLaura Fratiglioni
May 10, 2006·Archives of Internal Medicine·Cornelis S van der HooftBruno H Ch Stricker
Sep 18, 2007·Neurobiology of Aging·Andrew J Farrall, Joanna M Wardlaw
Dec 29, 2007·Journal of Cardiovascular Medicine·Peter Andrew, Annibale Sandro Montenero
Nov 1, 2008·The Journal of Pathology·M A WozniakR F Itzhaki
Feb 11, 2009·Scandinavian Journal of Clinical and Laboratory Investigation·Kristoffer Mads Aaris HenningsenJesper Hastrup Svendsen
Mar 28, 2009·The International Journal of Neuroscience·Jannis KountourasIfigenia Michailidou
May 20, 2009·Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research·Łukasz HakJan Rogowski
Jul 22, 2009·Ageing Research Reviews·María Dolores HerreraMaria Alvarez de Sotomayor
Aug 25, 2009·The Journal of Thoracic and Cardiovascular Surgery·Oliver J LiakopoulosThorsten Wahlers
Oct 14, 2009·Archives of Internal Medicine·Christian Fynbo ChristiansenHenrik Toft Sørensen
Dec 10, 2009·Dementia and Geriatric Cognitive Disorders·Orestes Vicente ForlenzaAntonio Lucio Teixeira
Feb 4, 2010·Heart Rhythm : the Official Journal of the Heart Rhythm Society·T Jared BunchJohn D Day
Feb 16, 2010·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Jie LiDawood Darbar
Feb 25, 2010·The Journal of Biological Chemistry·Antonella CaccamoSalvatore Oddo
May 4, 2010·Cardiovascular Therapeutics·Hong QiuNipavan Chiamvimonvat
Oct 19, 2010·Journal of the American College of Cardiology·Takashi KoyamaKazutaka Aonuma
Feb 25, 2011·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Irene SavelievaA John Camm
Apr 5, 2011·Neurobiology of Aging·Michal Schnaider BeeriVahram Haroutunian
Jul 26, 2011·International Journal of Cardiology·Chia-Hung ChiangHsin-Bang Leu
Aug 3, 2011·Journal of the American Geriatrics Society·Sascha DublinEric B Larson
Aug 9, 2011·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Bart MaesenUlrich Schotten
Nov 29, 2011·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Saurabh KumarPaul B Sparks

❮ Previous
Next ❯

Related Concepts

Related Feeds

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.

Atrial Filbrillation

Atrial fibrillation refers to the abnormal heart rhythm characterized by rapid and irregular beating of the atria. Here is the latest research.

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.