Inflammatory and nutritional statuses of patients submitted to resection of gastrointestinal tumors

Revista do Colégio Brasileiro de Cirurgiões
Ana Valéria Gonçalves FruchtenichtLuis Fernando Moreira

Abstract

to evaluate the association between the nutritional and the inflammatory statuses of patients with cancer of the gastrointestinal tract undergoing surgical resection and to identify predictors of mortality in these patients. we conducted a prospective study of 41 patients with gastrointestinal tract cancer submitted to surgery between October 2012 and December 2014. We evaluated the nutritional status by subjective and objective methods. We assessed the inflammatory response and prognosis using the modified Glasgow Prognostic Score (mGPS), Neutrophil/Lymphocyte Ratio (NLR), Onodera Prognostic Nutritional Index (mPNI), Inflammatory-Nutritional Index (INI) and C-Reactive Protein/Albumin ratio (mPINI). half of the patients were malnourished and 27% were at nutritional risk. There was a positive association between the percentage of weight loss (%WL) and the markers NLR (p=0.047), mPINI (p=0.014) and INI (p=0.015). Serum albumin levels (p=0.015), INI (p=0.026) and mPINI (p=0.026) were significantly associated with the PG-SGA categories. On multivariate analysis, albumin was the only inflammatory marker independently related to death (p=0.004). inflammatory markers were significantly associated with malnutrition, demonstrating that ...Continue Reading

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Oct 12, 2017·Revista do Colégio Brasileiro de Cirurgiões·Aline Kirjner PoziomyckLuis Fernando Moreira

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Citations

Sep 23, 2020·Nutrición hospitalaria·Vanusa Felício de SouzaValdete Regina Guandalini

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