Inflammatory aortitis in giant cell arteritis

La Presse médicale
Laurence Josselin-MahrJean Cabane

Abstract

A sub-clinical inflammatory aortitis is very frequent in patients with giant cell arteritis, and can be the only localization of the disease. In most patients, this aortitis is asymptomatic and is of no consequence on the patient's survival. The relative risk of developing an aortic dissection or aneurysm is 17.3. Evolution towards an aneurysm or an aortic dissection is unpredictable and rare; and seems independent of the disease activity and the associated vascular risk factors. Isolated aortitis treatment is not consensual, but often similar to the treatment of giant cell arteritis and adapted to clinical and biological markers of disease activity. Screening for sub-clinical aortitis with FDG-PET should not be prescribed in patients with typical presentation of giant cell arteritis. A systematic screening of aortic complications in giant cell arteritis patients could be done with a chest X-ray and an abdominal ultrasound possibly completed with an aortic CT-scan at time of diagnosis, in order to look for aneurysms with possible surgical indication.

References

Dec 1, 1975·Annals of Internal Medicine·R G KleinS G Sheps
Dec 1, 1995·Seminars in Arthritis and Rheumatism·G LiuB K Chiu
Nov 14, 1997·The New England Journal of Medicine·W A SchmidtE J Gromnica-Ihle
Feb 20, 1999·Arthritis and Rheumatism·A BrackC M Weyand
Apr 11, 2001·Archives of Internal Medicine·A TurlakowS M Larson
Oct 14, 2004·Annals of the Rheumatic Diseases·A K ScheelF Strutz
Dec 14, 2005·Current Opinion in Rheumatology·Tim Bongartz, Eric L Matteson
Aug 26, 2006·The American Journal of Surgical Pathology·James L HommeHenry D Tazelaar
Jun 17, 2008·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Hubertus HautzelHans-Wilhelm Müller
Jul 9, 2008·Scandinavian Cardiovascular Journal : SCJ·Ari A MennanderThoralf M Sundt
Aug 4, 2010·Journal of Cardiac Surgery·Nick ButlerPallav Shah
Dec 3, 2010·Current Opinion in Rheumatology·Augusto VaglioCarlo Salvarani
Jul 12, 2011·American Heart Journal·Anna M Booher, Kim A Eagle

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Citations

Sep 26, 2013·AJR. American Journal of Roentgenology·Ugur BozlarKlaus D Hagspiel
May 2, 2016·Reumatología clinica·M Del Pilar García-Cezón de la CruzPedro Zarco

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