Inflammatory bowel disease manifesting after surgical treatment for Hirschsprung disease

Journal of Pediatric Gastroenterology and Nutrition
David N LevinJacob C Langer

Abstract

Eight children developed chronic inflammatory bowel disease (IBD) 4 to 21 years after surgery for Hirschsprung disease. Three had trisomy 21 and 6 experienced chronic or recurrent enterocolitis. Four had a family history of IBD. Clinical presentation included chronic diarrhea, hematochezia, abscess, and fistula formation. Three required surgery for fistula, stricture, and small bowel obstruction and the other 5 were managed medically. Recognition of this condition may be important in the long-term follow-up of children with Hirschsprung disease, and patients who have carried a diagnosis of chronic enterocolitis may warrant further investigation looking for evidence of IBD.

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Citations

Jul 17, 2013·Current Gastroenterology Reports·Elizabeth M PontarelliChristopher P Gayer
Sep 19, 2012·Seminars in Pediatric Surgery·Philip K Frykman, Scott S Short
Sep 19, 2012·Seminars in Pediatric Surgery·Risto J Rintala, Mikko P Pakarinen
Aug 12, 2014·Journal of Crohn's & Colitis·Marie-Louise FrémondJean-Pierre Hugot
Sep 5, 2013·Clinical Pediatrics·Deepika D'Cunha BurkardtPhilip K Frykman
Sep 19, 2017·Journal of Pediatric Gastroenterology and Nutrition·Anna Löf GranströmTomas Wester
Apr 10, 2019·Journal of Pediatric Gastroenterology and Nutrition·Philip K FrykmanUNKNOWN HAEC Collaborative Research Group (HCRG)
Nov 20, 2016·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·Cécile O MullerArnaud Bonnard
Apr 28, 2020·ACG Case Reports Journal·Sharon Wolfson, Kristin Whitfield Van Buren
Feb 6, 2021·The Journal of Pediatrics·Charles N BernsteinEric I Benchimol
May 19, 2021·Inflammatory Bowel Diseases·Alessandra VerdePaolo Quitadamo

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