INFLAMMATORY CHOROIDAL NEOVASCULAR MEMBRANE: Long-Term Visual and Anatomical Outcomes After Intravitreal Anti-vascular Endothelial Growth Factor Therapy

Retina
Palmeera DʼsouzaVeerappan R Saravanan

Abstract

To assess the long-term visual and anatomical outcomes after intravitreal anti-vascular endothelial growth factor therapy for inflammatory choroidal neovascular membrane (CNVM). Retrospective case series of 15 consecutive cases of newly diagnosed inflammatory CNVM who were treated with intravitreal bevacizumab or ranibizumab injections. The study included 8 women and 7 men with mean age at presentation with CNVM of 40.53 ± 17.46 years (range, 11-70 years), and mean follow-up duration after anti-vascular endothelial growth factor therapy was 20.53 ± 14.53 months (range, 6-48 months). All eyes had classic CNVM confirmed by fluorescein angiography, most commonly located in the peripapillary area (8 eyes, 53.3%), followed by juxtafoveal (4 eyes, 26.7%), and subfoveal location (3 eyes, 20%). All CNVMs showed complete resolution with mean 2.6 ± 1.2 injections per eye. Preinjection mean best-corrected visual acuity of logarithm of minimum angle of resolution 0.79 ± 0.76 (approximate Snellen equivalent 20/123) and mean central macular thickness of 435.9 ± 190.2 μm improved significantly to mean best-corrected visual acuity of logarithm of minimum angle of resolution 0.46 ± 0.43 (approximate Snellen equivalent 20/58) and mean central ma...Continue Reading

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Citations

Aug 12, 2019·The British Journal of Ophthalmology·Sumit Randhir SinghJay Chhablani
Jun 20, 2020·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·Qiyu BoXiaodong Sun
Aug 17, 2019·Ocular Immunology and Inflammation·Pierre GasconThibaud Mathis
Nov 21, 2019·Ocular Immunology and Inflammation·Viviane M SakataJoyce H Yamamoto
Jul 6, 2020·Journal of Medical Case Reports·Chirag Jhaveri, Giovanni Campagna
Jul 24, 2021·American Journal of Ophthalmology·Mirinae KimYoung-Hoon Park
Oct 8, 2021·European Journal of Ophthalmology·Ratnesh RanjanNarendran Venkatapathy

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