Inflammatory choroidal neovascularization in Indian eyes: Etiology, clinical features, and outcomes to anti-vascular endothelial growth factor

Indian Journal of Ophthalmology
Rupak RoySwakshyar Saumya Paul

Abstract

The aim was to study the clinical profile of inflammatory choroidal neovascularization (CNV) and its treatment response to intravitreal bevacizumab or ranibizumab on pro re nata (PRN) basis in Indian eyes. This was a retrospective case series of consecutive patients with inflammatory CNV treated with anti-vascular endothelial growth factor (anti-VEGF) in a tertiary eye care center in Eastern India between 2009 and 2014. The data about clinical features, investigations, treatment, and outcomes were obtained from the medical records. We included patients with active inflammatory CNV but with no evidence of inflammation and were treated with anti-VEGF alone, with a minimum follow-up of 6 months. Main outcome measures were a clinical and etiological profile of inflammatory CNV in Indian eyes and their response to treatment. Thirty eyes of 28 patients were included in the study. The mean follow-up was 17.93 ± 14.28 months (range 6-53 months). In our cohort, seven (23.33%) eyes had inflammatory CNV secondary to idiopathic choroiditis, four (13.33%) eyes had toxoplasmosis, idiopathic panuveitis, and Vogt Koyanaki Harada's disease each. Three (10%) eyes had geographic helicoid peripapillary choroidopathy and tubercular choroiditis each...Continue Reading

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Citations

Feb 6, 2019·Clinical & Experimental Ophthalmology·Alessandro InvernizziGiovanni Staurenghi
Feb 1, 2020·Ocular Immunology and Inflammation·Emmett T CunninghamManfred Zierhut
Aug 12, 2019·The British Journal of Ophthalmology·Sumit Randhir SinghJay Chhablani
Sep 14, 2018·Journal of Ophthalmic Inflammation and Infection·Aniruddha AgarwalVishali Gupta
Feb 3, 2019·BMC Ophthalmology·Juanjuan LiLiwei Zhang
Nov 21, 2019·Ocular Immunology and Inflammation·Viviane M SakataJoyce H Yamamoto
Jan 8, 2021·Survey of Ophthalmology·Nazanin EbrahimiadibC Stephen Foster
Sep 13, 2019·Progress in Retinal and Eye Research·Francesco PichiMarion R Munk
Jul 24, 2021·American Journal of Ophthalmology·Mirinae KimYoung-Hoon Park

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Methods Mentioned

BETA
enzyme-linked immunosorbent assay

Software Mentioned

Statistical Package for Social Service ( SPSS

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