Abstract
The aim was to study the clinical profile of inflammatory choroidal neovascularization (CNV) and its treatment response to intravitreal bevacizumab or ranibizumab on pro re nata (PRN) basis in Indian eyes. This was a retrospective case series of consecutive patients with inflammatory CNV treated with anti-vascular endothelial growth factor (anti-VEGF) in a tertiary eye care center in Eastern India between 2009 and 2014. The data about clinical features, investigations, treatment, and outcomes were obtained from the medical records. We included patients with active inflammatory CNV but with no evidence of inflammation and were treated with anti-VEGF alone, with a minimum follow-up of 6 months. Main outcome measures were a clinical and etiological profile of inflammatory CNV in Indian eyes and their response to treatment. Thirty eyes of 28 patients were included in the study. The mean follow-up was 17.93 ± 14.28 months (range 6-53 months). In our cohort, seven (23.33%) eyes had inflammatory CNV secondary to idiopathic choroiditis, four (13.33%) eyes had toxoplasmosis, idiopathic panuveitis, and Vogt Koyanaki Harada's disease each. Three (10%) eyes had geographic helicoid peripapillary choroidopathy and tubercular choroiditis each...Continue Reading
References
Feb 15, 1987·American Journal of Ophthalmology·E Bloch-Michel, R B Nussenblatt
Sep 1, 1983·Archives of Ophthalmology
May 1, 1995·Ophthalmology·A C HoJ DeRosa
Aug 1, 1996·Ophthalmology·S Y CohenG J Coscas
Jul 31, 1998·Eye·C J FlaxelZ J Gregor
Nov 21, 1998·Archives of Ophthalmology·C DeesA D Dick
Jul 16, 2005·Ocular Immunology and Inflammation·Yannis PerentesCarl P Herbort
Jan 20, 2006·Ocular Immunology and Inflammation·Laurence PostelmansErica Smets
Oct 6, 2006·The New England Journal of Medicine·David M BrownUNKNOWN ANCHOR Study Group
Apr 21, 2007·The British Journal of Ophthalmology·Rohan W EssexG William Aylward
Apr 26, 2007·Indian Journal of Ophthalmology·S R Rathinam, P Namperumalsamy
Nov 30, 2007·Retina·Alfredo AdánRicardo P Casaroli-Marano
Jan 11, 2008·Retina·Wai-Man ChanDennis S C Lam
May 12, 2009·American Journal of Ophthalmology·Ahmad M MansourRainer Guthoff
Feb 20, 2010·Retina·Michal KramerRadgonde Amer
Aug 4, 2010·Ophthalmology·Jeffrey S HeierIvana K Kim
Oct 5, 2010·Retina·J Fernando ArevaloUNKNOWN Pan-American Collaborative Retina Study Group
Dec 16, 2010·Indian Journal of Ophthalmology·Pukhraj RishiEkta Rishi
Feb 26, 2011·Indian Journal of Ophthalmology·Vinita G RaoNilesh S Narkhede
Mar 2, 2011·Retina·Alexander RouvasNikolaos Markomichelakis
Jun 15, 2011·Indian Journal of Ophthalmology·Nikunj J Shah, Urmi N Shah
Jun 26, 2013·American Journal of Ophthalmology·Sally L BaxterJohn H Kempen
Dec 4, 2015·Indian Journal of Ophthalmology·Dipankar DasRajashree Paul
Citations
Feb 6, 2019·Clinical & Experimental Ophthalmology·Alessandro InvernizziGiovanni Staurenghi
Feb 1, 2020·Ocular Immunology and Inflammation·Emmett T CunninghamManfred Zierhut
Aug 12, 2019·The British Journal of Ophthalmology·Sumit Randhir SinghJay Chhablani
Sep 14, 2018·Journal of Ophthalmic Inflammation and Infection·Aniruddha AgarwalVishali Gupta
Feb 3, 2019·BMC Ophthalmology·Juanjuan LiLiwei Zhang
Nov 21, 2019·Ocular Immunology and Inflammation·Viviane M SakataJoyce H Yamamoto
Jan 8, 2021·Survey of Ophthalmology·Nazanin EbrahimiadibC Stephen Foster
Sep 13, 2019·Progress in Retinal and Eye Research·Francesco PichiMarion R Munk
Jul 24, 2021·American Journal of Ophthalmology·Mirinae KimYoung-Hoon Park